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Structural insights into the HBV receptor and bile acid transporter NTCP.
Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY. Park JH, et al. Among authors: wakita t. Nature. 2022 Jun;606(7916):1027-1031. doi: 10.1038/s41586-022-04857-0. Epub 2022 May 17. Nature. 2022. PMID: 35580630 Free PMC article.
The lipid droplet is an important organelle for hepatitis C virus production.
Miyanari Y, Atsuzawa K, Usuda N, Watashi K, Hishiki T, Zayas M, Bartenschlager R, Wakita T, Hijikata M, Shimotohno K. Miyanari Y, et al. Among authors: wakita t. Nat Cell Biol. 2007 Sep;9(9):1089-97. doi: 10.1038/ncb1631. Epub 2007 Aug 26. Nat Cell Biol. 2007. PMID: 17721513
Antiviral activity of glycyrrhizin against hepatitis C virus in vitro.
Matsumoto Y, Matsuura T, Aoyagi H, Matsuda M, Hmwe SS, Date T, Watanabe N, Watashi K, Suzuki R, Ichinose S, Wake K, Suzuki T, Miyamura T, Wakita T, Aizaki H. Matsumoto Y, et al. Among authors: wakita t. PLoS One. 2013 Jul 18;8(7):e68992. doi: 10.1371/journal.pone.0068992. Print 2013. PLoS One. 2013. PMID: 23874843 Free PMC article.
Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID).
Watashi K, Liang G, Iwamoto M, Marusawa H, Uchida N, Daito T, Kitamura K, Muramatsu M, Ohashi H, Kiyohara T, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T. Watashi K, et al. Among authors: wakita t. J Biol Chem. 2013 Nov 1;288(44):31715-27. doi: 10.1074/jbc.M113.501122. Epub 2013 Sep 11. J Biol Chem. 2013. PMID: 24025329 Free PMC article.
Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.
Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T. Iwamoto M, et al. Among authors: wakita t. Biochem Biophys Res Commun. 2014 Jan 17;443(3):808-13. doi: 10.1016/j.bbrc.2013.12.052. Epub 2013 Dec 14. Biochem Biophys Res Commun. 2014. PMID: 24342612 Free article.
Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP).
Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T. Watashi K, et al. Among authors: wakita t. Hepatology. 2014 May;59(5):1726-37. doi: 10.1002/hep.26982. Epub 2014 Apr 1. Hepatology. 2014. PMID: 24375637 Free PMC article.
624 results