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Tandem chimeric antigen receptor (CAR) T cells targeting EGFRvIII and IL-13Rα2 are effective against heterogeneous glioblastoma.
Schmidts A, Srivastava AA, Ramapriyan R, Bailey SR, Bouffard AA, Cahill DP, Carter BS, Curry WT, Dunn GP, Frigault MJ, Gerstner ER, Ghannam JY, Kann MC, Larson RC, Leick MB, Nahed BV, Richardson LG, Scarfò I, Sun J, Wakimoto H, Maus MV, Choi BD. Schmidts A, et al. Among authors: wakimoto h. Neurooncol Adv. 2022 Dec 22;5(1):vdac185. doi: 10.1093/noajnl/vdac185. eCollection 2023 Jan-Dec. Neurooncol Adv. 2022. PMID: 36751672 Free PMC article.
Genetic alterations that deregulate RB and PDGFRA signaling pathways drive tumor progression in IDH2-mutant astrocytoma.
Tateishi K, Miyake Y, Nakamura T, Iwashita H, Hayashi T, Oshima A, Honma H, Hayashi H, Sugino K, Kato M, Satomi K, Fujii S, Komori T, Yamamoto T, Cahill DP, Wakimoto H. Tateishi K, et al. Among authors: wakimoto h. Acta Neuropathol Commun. 2023 Nov 27;11(1):186. doi: 10.1186/s40478-023-01683-x. Acta Neuropathol Commun. 2023. PMID: 38012788 Free PMC article.
Genetic characterization and mutational profiling of foramen magnum meningiomas: a multi-institutional study.
Hua L, Alkhatib M, Fujio S, Alhasan B, Herold S, Zeugner S, Zolal A, Hijazi MM, Clark VE, Wakimoto H, Shankar GM, Brastianos PK, Barker FG, Cahill DP, Ren L, Eyüpoglu IY, Gong Y, Schackert G, Juratli TA. Hua L, et al. Among authors: wakimoto h. J Neurosurg. 2024 Jan 26:1-7. doi: 10.3171/2023.11.JNS231936. Online ahead of print. J Neurosurg. 2024. PMID: 38277657
Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma.
Spitzer A, Gritsch S, Nomura M, Jucht A, Fortin J, Raviram R, Weisman HR, Gonzalez Castro LN, Druck N, Chanoch-Myers R, Lee JJY, Mylvaganam R, Lee Servis R, Fung JM, Lee CK, Nagashima H, Miller JJ, Arrillaga-Romany I, Louis DN, Wakimoto H, Pisano W, Wen PY, Mak TW, Sanson M, Touat M, Landau DA, Ligon KL, Cahill DP, Suvà ML, Tirosh I. Spitzer A, et al. Among authors: wakimoto h. Cancer Cell. 2024 May 13;42(5):904-914.e9. doi: 10.1016/j.ccell.2024.03.008. Epub 2024 Apr 4. Cancer Cell. 2024. PMID: 38579724
307 results