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The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ.
Yang Y, Yang HH, Tang B, Wu AML, Flanders KC, Moshkovich N, Weinberg DS, Welsh MA, Weng J, Ochoa HJ, Hu TY, Herrmann MA, Chen J, Edmondson EF, Simpson RM, Liu F, Liu H, Lee MP, Wakefield LM. Yang Y, et al. Among authors: wakefield lm. Clin Cancer Res. 2020 Feb 1;26(3):643-656. doi: 10.1158/1078-0432.CCR-19-2370. Epub 2019 Oct 3. Clin Cancer Res. 2020. PMID: 31582516 Free PMC article.
Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA.
Kadota M, Sato M, Duncan B, Ooshima A, Yang HH, Diaz-Meyer N, Gere S, Kageyama S, Fukuoka J, Nagata T, Tsukada K, Dunn BK, Wakefield LM, Lee MP. Kadota M, et al. Among authors: wakefield lm. Cancer Res. 2009 Sep 15;69(18):7357-65. doi: 10.1158/0008-5472.CAN-09-0064. Epub 2009 Aug 25. Cancer Res. 2009. PMID: 19706770 Free PMC article.
Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination.
Sharma VP, Tang B, Wang Y, Duran CL, Karagiannis GS, Xue EA, Entenberg D, Borriello L, Coste A, Eddy RJ, Kim G, Ye X, Jones JG, Grunblatt E, Agi N, Roy S, Bandyopadhyaya G, Adler E, Surve CR, Esposito D, Goswami S, Segall JE, Guo W, Condeelis JS, Wakefield LM, Oktay MH. Sharma VP, et al. Among authors: wakefield lm. Nat Commun. 2021 Dec 15;12(1):7300. doi: 10.1038/s41467-021-27308-2. Nat Commun. 2021. PMID: 34911937 Free PMC article.
Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis.
Wu AML, Gossa S, Samala R, Chung MA, Gril B, Yang HH, Thorsheim HR, Tran AD, Wei D, Taner E, Isanogle K, Yang Y, Dolan EL, Robinson C, Difilippantonio S, Lee MP, Khan I, Smith QR, McGavern DB, Wakefield LM, Steeg PS. Wu AML, et al. Among authors: wakefield lm. Clin Cancer Res. 2021 Aug 1;27(15):4422-4434. doi: 10.1158/1078-0432.CCR-21-1549. Epub 2021 Jun 3. Clin Cancer Res. 2021. PMID: 34083229 Free PMC article.
153 results