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Induction of a Proinflammatory Response in Cortical Astrocytes by the Major Metabolites Accumulating in HMG-CoA Lyase Deficiency: the Role of ERK Signaling Pathway in Cytokine Release.
Fernandes CG, Rodrigues MDN, Seminotti B, Colín-González AL, Santamaria A, Quincozes-Santos A, Wajner M. Fernandes CG, et al. Among authors: wajner m. Mol Neurobiol. 2016 Aug;53(6):3586-3595. doi: 10.1007/s12035-015-9289-9. Epub 2015 Jun 23. Mol Neurobiol. 2016. PMID: 26099308
Ornithine and Homocitrulline Impair Mitochondrial Function, Decrease Antioxidant Defenses and Induce Cell Death in Menadione-Stressed Rat Cortical Astrocytes: Potential Mechanisms of Neurological Dysfunction in HHH Syndrome.
Zanatta Â, Rodrigues MD, Amaral AU, Souza DG, Quincozes-Santos A, Wajner M. Zanatta Â, et al. Among authors: wajner m. Neurochem Res. 2016 Sep;41(9):2190-8. doi: 10.1007/s11064-016-1933-x. Epub 2016 May 9. Neurochem Res. 2016. PMID: 27161368
Higher Vulnerability of Menadione-Exposed Cortical Astrocytes of Glutaryl-CoA Dehydrogenase Deficient Mice to Oxidative Stress, Mitochondrial Dysfunction, and Cell Death: Implications for the Neurodegeneration in Glutaric Aciduria Type I.
Rodrigues MDN, Seminotti B, Zanatta Â, de Mello Gonçalves A, Bellaver B, Amaral AU, Quincozes-Santos A, Goodman SI, Woontner M, Souza DO, Wajner M. Rodrigues MDN, et al. Among authors: wajner m. Mol Neurobiol. 2017 Aug;54(6):4795-4805. doi: 10.1007/s12035-016-0023-z. Epub 2016 Aug 10. Mol Neurobiol. 2017. PMID: 27510504
Bioenergetics dysfunction, mitochondrial permeability transition pore opening and lipid peroxidation induced by hydrogen sulfide as relevant pathomechanisms underlying the neurological dysfunction characteristic of ethylmalonic encephalopathy.
Cardoso GMF, Pletsch JT, Parmeggiani B, Grings M, Glanzel NM, Bobermin LD, Amaral AU, Wajner M, Leipnitz G. Cardoso GMF, et al. Among authors: wajner m. Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2192-2201. doi: 10.1016/j.bbadis.2017.06.007. Epub 2017 Jun 15. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28624490 Free article.
Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum.
de Moura Alvorcem L, Britto R, Parmeggiani B, Glanzel NM, da Rosa-Junior NT, Cecatto C, Bobermin LD, Amaral AU, Wajner M, Leipnitz G. de Moura Alvorcem L, et al. Among authors: wajner m. Mitochondrion. 2019 Jul;47:141-150. doi: 10.1016/j.mito.2018.11.001. Epub 2018 Nov 3. Mitochondrion. 2019. PMID: 30399433
476 results