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Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer's Disease Mouse Model with Humanized TNF Receptor 2.
Ortí-Casañ N, Wajant H, Kuiperij HB, Hooijsma A, Tromp L, Poortman IL, Tadema N, de Lange JHE, Verbeek MM, De Deyn PP, Naudé PJW, Eisel ULM. Ortí-Casañ N, et al. Among authors: wajant h. J Alzheimers Dis. 2023;94(3):977-991. doi: 10.3233/JAD-221230. J Alzheimers Dis. 2023. PMID: 37355890 Free PMC article.
Systemic treatment with a selective TNFR2 agonist alters the central and peripheral immune responses and transiently improves functional outcome after experimental ischemic stroke.
Thougaard E, Nielsen PV, Forsberg A, Phuong V, Velasco AM, Wlodarczyk A, Wajant H, Lang I, Mikkelsen JD, Clausen BH, Brambilla R, Lambertsen KL. Thougaard E, et al. Among authors: wajant h. J Neuroimmunol. 2023 Dec 15;385:578246. doi: 10.1016/j.jneuroim.2023.578246. Epub 2023 Nov 17. J Neuroimmunol. 2023. PMID: 37988839 Free article.
Corrigendum: A TNFR2-specific TNF fusion protein with improved in vivo activity.
Gamboa Vargas J, Wagner J, Shaikh H, Lang I, Medler J, Anany M, Steinfatt T, Peña Mosca J, Haack S, Dahlhoff J, Büttner-Herold M, Graf C, Viera EA, Einsele H, Wajant H, Beilhack A. Gamboa Vargas J, et al. Among authors: wajant h. Front Immunol. 2023 Dec 18;14:1352525. doi: 10.3389/fimmu.2023.1352525. eCollection 2023. Front Immunol. 2023. PMID: 38164131 Free PMC article.
Generic design principles for antibody-based tumour necrosis factor (TNF) receptor 2 (TNFR2) agonists with FcγR-independent agonism.
Anany MA, Haack S, Lang I, Dahlhoff J, Vargas JG, Steinfatt T, Päckert L, Weisenberger D, Zaitseva O, Medler J, Kucka K, Zhang T, Van Belle T, van Rompaey L, Beilhack A, Wajant H. Anany MA, et al. Among authors: wajant h. Theranostics. 2024 Jan 1;14(2):496-509. doi: 10.7150/thno.84404. eCollection 2024. Theranostics. 2024. PMID: 38169605 Free PMC article.
Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling.
Siegmund D, Zaitseva O, Wajant H. Siegmund D, et al. Among authors: wajant h. Front Cell Dev Biol. 2023 Nov 6;11:1267837. doi: 10.3389/fcell.2023.1267837. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020877 Free PMC article. Review.
213 results