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IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts.
Picard FSR, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle PI, Savai R, Prinz I, Waisman A, Moos S, Chang HD, Heinrich S, Bartsch DK, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung HR, Mayer P, Gress TM, Lauth M, Gaida M, Huber M. Picard FSR, et al. Among authors: waisman a. Gut. 2023 Aug;72(8):1510-1522. doi: 10.1136/gutjnl-2022-327855. Epub 2023 Feb 9. Gut. 2023. PMID: 36759154 Free PMC article.
Protein kinase CK2 governs the molecular decision between encephalitogenic TH17 cell and Treg cell development.
Ulges A, Witsch EJ, Pramanik G, Klein M, Birkner K, Bühler U, Wasser B, Luessi F, Stergiou N, Dietzen S, Brühl TJ, Bohn T, Bündgen G, Kunz H, Waisman A, Schild H, Schmitt E, Zipp F, Bopp T. Ulges A, et al. Among authors: waisman a. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10145-50. doi: 10.1073/pnas.1523869113. Epub 2016 Aug 23. Proc Natl Acad Sci U S A. 2016. PMID: 27555590 Free PMC article.
Expression of IL-17F is associated with non-pathogenic Th17 cells.
Wanke F, Tang Y, Gronke K, Klebow S, Moos S, Hauptmann J, Shanmugavadivu A, Regen T, Mufazalov IA, Gabriel LA, Reißig S, Diefenbach A, Kurschus FC, Waisman A. Wanke F, et al. Among authors: waisman a. J Mol Med (Berl). 2018 Aug;96(8):819-829. doi: 10.1007/s00109-018-1662-5. Epub 2018 Jun 29. J Mol Med (Berl). 2018. PMID: 29959474
NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling.
Lacher SM, Thurm C, Distler U, Mohebiany AN, Israel N, Kitic M, Ebering A, Tang Y, Klein M, Wabnitz GH, Wanke F, Samstag Y, Bopp T, Kurschus FC, Simeoni L, Tenzer S, Waisman A. Lacher SM, et al. Among authors: waisman a. J Autoimmun. 2018 Nov;94:110-121. doi: 10.1016/j.jaut.2018.07.017. Epub 2018 Jul 29. J Autoimmun. 2018. PMID: 30061013
Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology.
Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein M, Marini F, Kreutzfeldt M, Härtner F, Lacher SM, Bopp T, Mittmann T, Merkler D, Waisman A. Mohebiany AN, et al. Among authors: waisman a. Cell Rep. 2020 Feb 4;30(5):1585-1597.e6. doi: 10.1016/j.celrep.2019.12.097. Cell Rep. 2020. PMID: 32023471 Free article.
Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer.
Salazar Y, Zheng X, Brunn D, Raifer H, Picard F, Zhang Y, Winter H, Guenther S, Weigert A, Weigmann B, Dumoutier L, Renauld JC, Waisman A, Schmall A, Tufman A, Fink L, Brüne B, Bopp T, Grimminger F, Seeger W, Pullamsetti SS, Huber M, Savai R. Salazar Y, et al. Among authors: waisman a. J Clin Invest. 2020 Jul 1;130(7):3560-3575. doi: 10.1172/JCI124037. J Clin Invest. 2020. PMID: 32229721 Free PMC article.
349 results