Waight AB - Search Results

1

Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability.

Goulet DR, Chatterjee S, Lee WP, Waight AB, Zhu Y, Mak AN. Goulet DR, et al. Among authors: waight ab. Antibodies (Basel). 2022 Jan 13;11(1):6. doi: 10.3390/antib11010006. Antibodies (Basel). 2022. PMID: 35076451 Free PMC article.

2

ACE2-Fc fusion protein overcomes viral escape by potently neutralizing SARS-CoV-2 variants of concern.

Tsai TI, Khalili JS, Gilchrist M, Waight AB, Cohen D, Zhuo S, Zhang Y, Ding M, Zhu H, Mak AN, Zhu Y, Goulet DR. Tsai TI, et al. Among authors: waight ab. Antiviral Res. 2022 Mar;199:105271. doi: 10.1016/j.antiviral.2022.105271. Epub 2022 Feb 28. Antiviral Res. 2022. PMID: 35240221 Free PMC article.

3

Codon Optimization Using a Recurrent Neural Network.

Goulet DR, Yan Y, Agrawal P, Waight AB, Mak AN, Zhu Y. Goulet DR, et al. Among authors: waight ab. J Comput Biol. 2023 Jan;30(1):70-81. doi: 10.1089/cmb.2021.0458. Epub 2022 Jun 21. J Comput Biol. 2023. PMID: 35727687

4

BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning.

Prihoda D, Maamary J, Waight A, Juan V, Fayadat-Dilman L, Svozil D, Bitton DA. Prihoda D, et al. MAbs. 2022 Jan-Dec;14(1):2020203. doi: 10.1080/19420862.2021.2020203. MAbs. 2022. PMID: 35133949 Free PMC article.

5

A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties.

Waight AB, Prihoda D, Shrestha R, Metcalf K, Bailly M, Ancona M, Widatalla T, Rollins Z, Cheng AC, Bitton DA, Fayadat-Dilman L. Waight AB, et al. MAbs. 2023 Jan-Dec;15(1):2248671. doi: 10.1080/19420862.2023.2248671. MAbs. 2023. PMID: 37610144 Free PMC article.

6

Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation.

Hamilton JZ, Pires TA, Mitchell JA, Cochran JH, Emmerton KK, Zaval M, Stone IJ, Anderson ME, Jin S, Waight AB, Lyon RP, Senter PD, Jeffrey SC, Burke PJ. Hamilton JZ, et al. Among authors: waight ab. ChemMedChem. 2021 Apr 8;16(7):1077-1081. doi: 10.1002/cmdc.202000889. Epub 2021 Feb 12. ChemMedChem. 2021. PMID: 33369163 Free PMC article.

7

Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux-positive Tumor Models.

Moquist PN, Bovee TD, Waight AB, Mitchell JA, Miyamoto JB, Mason ML, Emmerton KK, Stevens N, Balasubramanian C, Simmons JK, Lyon RP, Senter PD, Doronina SO. Moquist PN, et al. Among authors: waight ab. Mol Cancer Ther. 2021 Feb;20(2):320-328. doi: 10.1158/1535-7163.MCT-20-0618. Epub 2020 Dec 7. Mol Cancer Ther. 2021. PMID: 33288628

8

Structure-activity relationships of tubulysin analogues.

Courter JR, Hamilton JZ, Hendrick NR, Zaval M, Waight AB, Lyon RP, Senter PD, Jeffrey SC, Burke PJ. Courter JR, et al. Among authors: waight ab. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127241. doi: 10.1016/j.bmcl.2020.127241. Epub 2020 May 5. Bioorg Med Chem Lett. 2020. PMID: 32527543

9

Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody-Drug Conjugates.

Neumann CS, Olivas KC, Anderson ME, Cochran JH, Jin S, Li F, Loftus LV, Meyer DW, Neale J, Nix JC, Pittman PG, Simmons JK, Ulrich ML, Waight AB, Wong A, Zaval MC, Zeng W, Lyon RP, Senter PD. Neumann CS, et al. Among authors: waight ab. Mol Cancer Ther. 2018 Dec;17(12):2633-2642. doi: 10.1158/1535-7163.MCT-18-0643. Epub 2018 Sep 21. Mol Cancer Ther. 2018. PMID: 30242091

10

Glucuronide-Linked Antibody-Tubulysin Conjugates Display Activity in MDR⁺ and Heterogeneous Tumor Models.

Burke PJ, Hamilton JZ, Pires TA, Lai HWH, Leiske CI, Emmerton KK, Waight AB, Senter PD, Lyon RP, Jeffrey SC. Burke PJ, et al. Among authors: waight ab. Mol Cancer Ther. 2018 Aug;17(8):1752-1760. doi: 10.1158/1535-7163.MCT-18-0073. Epub 2018 Jun 4. Mol Cancer Ther. 2018. PMID: 29866744

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