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Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.
Isaguliants M, Smirnova O, Ivanov AV, Kilpelainen A, Kuzmenko Y, Petkov S, Latanova A, Krotova O, Engström G, Karpov V, Kochetkov S, Wahren B, Starodubova E. Isaguliants M, et al. Among authors: wahren b. Hum Vaccin Immunother. 2013 Oct;9(10):2111-9. doi: 10.4161/hv.25813. Epub 2013 Jul 23. Hum Vaccin Immunother. 2013. PMID: 23881028 Free PMC article.
Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.
Latanova AA, Petkov S, Kilpelainen A, Jansons J, Latyshev OE, Kuzmenko YV, Hinkula J, Abakumov MA, Valuev-Elliston VT, Gomelsky M, Karpov VL, Chiodi F, Wahren B, Logunov DY, Starodubova ES, Isaguliants MG. Latanova AA, et al. Among authors: wahren b. Sci Rep. 2018 May 24;8(1):8078. doi: 10.1038/s41598-018-26281-z. Sci Rep. 2018. PMID: 29799015 Free PMC article.
Gene immunization may induce secondary antibodies reacting with DNA.
Isaguliants MG, Iakimtchouk K, Petrakova NV, Yermalovich MA, Zuber AK, Kashuba VI, Belikov SV, Andersson S, Kochetkov SN, Klinman DM, Wahren B. Isaguliants MG, et al. Among authors: wahren b. Vaccine. 2004 Mar 29;22(11-12):1576-85. doi: 10.1016/j.vaccine.2003.09.033. Vaccine. 2004. PMID: 15063584
546 results