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Reinvestigation of Passerini and Ugi scaffolds as multistep apoptotic inducers via dual modulation of caspase 3/7 and P53-MDM2 signaling for halting breast cancer.
RSC Adv. 2023 Sep 20;13(40):27722-27737. doi: 10.1039/d3ra04029a. eCollection 2023 Sep 18.
RSC Adv. 2023.
PMID: 37736568
Free PMC article.
Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators.
Ayoup MS, Wahby Y, Abdel-Hamid H, Abu-Serie MM, Teleb M.
Ayoup MS, et al. Among authors: wahby y.
Sci Rep. 2022 Dec 27;12(1):22390. doi: 10.1038/s41598-022-26469-4.
Sci Rep. 2022.
PMID: 36575196
Free PMC article.
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Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators.
Salah Ayoup M, Wahby Y, Abdel-Hamid H, Ramadan ES, Teleb M, Abu-Serie MM, Noby A.
Salah Ayoup M, et al. Among authors: wahby y.
Eur J Med Chem. 2019 Apr 15;168:340-356. doi: 10.1016/j.ejmech.2019.02.051. Epub 2019 Feb 22.
Eur J Med Chem. 2019.
PMID: 30826510
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