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Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner.
Sag CM, Mallwitz A, Wagner S, Hartmann N, Schotola H, Fischer TH, Ungeheuer N, Herting J, Shah AM, Maier LS, Sossalla S, Unsöld B. Sag CM, et al. Among authors: wagner s. J Mol Cell Cardiol. 2014 Nov;76:94-105. doi: 10.1016/j.yjmcc.2014.08.016. Epub 2014 Aug 27. J Mol Cell Cardiol. 2014. PMID: 25173923
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. Among authors: wagner s. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Empagliflozin directly improves diastolic function in human heart failure.
Pabel S, Wagner S, Bollenberg H, Bengel P, Kovács Á, Schach C, Tirilomis P, Mustroph J, Renner A, Gummert J, Fischer T, Van Linthout S, Tschöpe C, Streckfuss-Bömeke K, Hasenfuss G, Maier LS, Hamdani N, Sossalla S. Pabel S, et al. Among authors: wagner s. Eur J Heart Fail. 2018 Dec;20(12):1690-1700. doi: 10.1002/ejhf.1328. Epub 2018 Oct 17. Eur J Heart Fail. 2018. PMID: 30328645 Free article.
NCX1 represents an ionic Na+ sensing mechanism in macrophages.
Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. Neubert P, et al. Among authors: wagner s. PLoS Biol. 2020 Jun 22;18(6):e3000722. doi: 10.1371/journal.pbio.3000722. eCollection 2020 Jun. PLoS Biol. 2020. PMID: 32569301 Free PMC article.
Enhanced Heart Failure in Redox-Dead Cys17Ser PKARIα Knock-In Mice.
Islam MMT, Tarnowski D, Zhang M, Trum M, Lebek S, Mustroph J, Daniel H, Moellencamp J, Pabel S, Sossalla S, El-Armouche A, Nikolaev VO, Shah AM, Eaton P, Maier LS, Sag CM, Wagner S. Islam MMT, et al. Among authors: wagner s. J Am Heart Assoc. 2021 Oct 5;10(19):e021985. doi: 10.1161/JAHA.121.021985. Epub 2021 Sep 29. J Am Heart Assoc. 2021. PMID: 34583520 Free PMC article.
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure.
Bengel P, Dybkova N, Tirilomis P, Ahmad S, Hartmann N, A Mohamed B, Krekeler MC, Maurer W, Pabel S, Trum M, Mustroph J, Gummert J, Milting H, Wagner S, Ljubojevic-Holzer S, Toischer K, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S. Bengel P, et al. Among authors: wagner s. Nat Commun. 2021 Nov 15;12(1):6586. doi: 10.1038/s41467-021-26690-1. Nat Commun. 2021. PMID: 34782600 Free PMC article.
3,886 results