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CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.
Neo SY, Yang Y, Record J, Ma R, Chen X, Chen Z, Tobin NP, Blake E, Seitz C, Thomas R, Wagner AK, Andersson J, de Boniface J, Bergh J, Murray S, Alici E, Childs R, Johansson M, Westerberg LS, Haglund F, Hartman J, Lundqvist A. Neo SY, et al. Among authors: wagner ak. J Clin Invest. 2020 Mar 2;130(3):1185-1198. doi: 10.1172/JCI128895. J Clin Invest. 2020. PMID: 31770109 Free PMC article.
Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells.
Kritikou JS, Oliveira MM, Record J, Saeed MB, Nigam SM, He M, Keszei M, Wagner AK, Brauner H, Sendel A, Sedimbi SK, Rentouli S, Lane DP, Snapper SB, Kärre K, Vandenberghe P, Orange JS, Westerberg LS. Kritikou JS, et al. Among authors: wagner ak. JCI Insight. 2021 Mar 22;6(6):e140273. doi: 10.1172/jci.insight.140273. JCI Insight. 2021. PMID: 33621210 Free PMC article.
328 results