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PEG conjugates of potent α4 integrin inhibitors, maintaining sustained levels and bioactivity in vivo, following subcutaneous administration.
Smith JL, Rossiter KI, Semko CM, Xu YZ, Quincy DA, Jagodzinski J, Dappen MS, Konradi AW, Vandevert C, Garrido C, Mao W, San Pablo FB, Wipke B, Dofiles L, Wadsworth A, Peterson E, Lorenzana C, Simmonds S, Messersmith EK, Bard F, Pleiss MA, Yednock TA. Smith JL, et al. Among authors: wadsworth a. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4117-9. doi: 10.1016/j.bmcl.2013.05.048. Epub 2013 May 24. Bioorg Med Chem Lett. 2013. PMID: 23743283
Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.
Hawkinson JE, Szoke BG, Garofalo AW, Hom DS, Zhang H, Dreyer M, Fukuda JY, Chen L, Samant B, Simmonds S, Zeitz KP, Wadsworth A, Liao A, Chavez RA, Zmolek W, Ruslim L, Bova MP, Holcomb R, Butelman ER, Ko MC, Malmberg AB. Hawkinson JE, et al. Among authors: wadsworth a. J Pharmacol Exp Ther. 2007 Aug;322(2):619-30. doi: 10.1124/jpet.107.120352. Epub 2007 Apr 30. J Pharmacol Exp Ther. 2007. PMID: 17470643
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation.
Harris PWR, Siow A, Yang SH, Wadsworth AD, Tan L, Hermant Y, Mao Y, An C, Hanna CC, Cameron AJ, Allison JR, Chakraborty A, Ferguson SA, Mros S, Hards K, Cook GM, Williamson DA, Carter GP, Chan STS, Painter GA, Sander V, Davidson AJ, Brimble MA. Harris PWR, et al. Among authors: wadsworth ad. ACS Infect Dis. 2022 Dec 9;8(12):2413-2429. doi: 10.1021/acsinfecdis.1c00347. Epub 2022 Nov 22. ACS Infect Dis. 2022. PMID: 36413173
Adjusting the energy of interfacial states in organic photovoltaics for maximum efficiency.
Gasparini N, Camargo FVA, Frühwald S, Nagahara T, Classen A, Roland S, Wadsworth A, Gregoriou VG, Chochos CL, Neher D, Salvador M, Baran D, McCulloch I, Görling A, Lüer L, Cerullo G, Brabec CJ. Gasparini N, et al. Among authors: wadsworth a. Nat Commun. 2021 Mar 19;12(1):1772. doi: 10.1038/s41467-021-22032-3. Nat Commun. 2021. PMID: 33741966 Free PMC article.
Acene Ring Size Optimization in Fused Lactam Polymers Enabling High n-Type Organic Thermoelectric Performance.
Chen H, Moser M, Wang S, Jellett C, Thorley K, Harrison GT, Jiao X, Xiao M, Purushothaman B, Alsufyani M, Bristow H, De Wolf S, Gasparini N, Wadsworth A, McNeill CR, Sirringhaus H, Fabiano S, McCulloch I. Chen H, et al. Among authors: wadsworth a. J Am Chem Soc. 2021 Jan 13;143(1):260-268. doi: 10.1021/jacs.0c10365. Epub 2020 Dec 22. J Am Chem Soc. 2021. PMID: 33350307
Polaron Delocalization in Donor-Acceptor Polymers and its Impact on Organic Electrochemical Transistor Performance.
Moser M, Savva A, Thorley K, Paulsen BD, Hidalgo TC, Ohayon D, Chen H, Giovannitti A, Marks A, Gasparini N, Wadsworth A, Rivnay J, Inal S, McCulloch I. Moser M, et al. Among authors: wadsworth a. Angew Chem Int Ed Engl. 2021 Mar 29;60(14):7777-7785. doi: 10.1002/anie.202014078. Epub 2021 Feb 26. Angew Chem Int Ed Engl. 2021. PMID: 33259685
91 results