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Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes.
Ledsgaard L, Wade J, Jenkins TP, Boddum K, Oganesyan I, Harrison JA, Villar P, Leah RA, Zenobi R, Schoffelen S, Voldborg B, Ljungars A, McCafferty J, Lomonte B, Gutiérrez JM, Laustsen AH, Karatt-Vellatt A. Ledsgaard L, et al. Among authors: wade j. Nat Commun. 2023 Feb 8;14(1):682. doi: 10.1038/s41467-023-36393-4. Nat Commun. 2023. PMID: 36755049 Free PMC article.
Advances in antibody phage display technology.
Ledsgaard L, Ljungars A, Rimbault C, Sørensen CV, Tulika T, Wade J, Wouters Y, McCafferty J, Laustsen AH. Ledsgaard L, et al. Among authors: wade j. Drug Discov Today. 2022 Aug;27(8):2151-2169. doi: 10.1016/j.drudis.2022.05.002. Epub 2022 May 10. Drug Discov Today. 2022. PMID: 35550436 Free article. Review.
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom.
Ledsgaard L, Laustsen AH, Pus U, Wade J, Villar P, Boddum K, Slavny P, Masters EW, Arias AS, Oscoz S, Griffiths DT, Luther AM, Lindholm M, Leah RA, Møller MS, Ali H, McCafferty J, Lomonte B, Gutiérrez JM, Karatt-Vellatt A. Ledsgaard L, et al. Among authors: wade j. MAbs. 2022 Jan-Dec;14(1):2085536. doi: 10.1080/19420862.2022.2085536. MAbs. 2022. PMID: 35699567 Free PMC article.
Phase III Randomized, Placebo-Controlled Clinical Trial of Donepezil for Treatment of Cognitive Impairment in Breast Cancer Survivors After Adjuvant Chemotherapy (WF-97116).
Rapp SR, Dressler EV, Brown WM, Wade JL 3rd, Le-Lindqwister N, King D, Rowland KM, Weaver KE, Klepin HD, Shaw EG, Lesser GJ. Rapp SR, et al. Among authors: wade jl 3rd. J Clin Oncol. 2024 May 6:JCO2301100. doi: 10.1200/JCO.23.01100. Online ahead of print. J Clin Oncol. 2024. PMID: 38709986
Covariate modeling in pharmacometrics: General points for consideration.
Sanghavi K, Ribbing J, Rogers JA, Ahmed MA, Karlsson MO, Holford N, Chasseloup E, Ahamadi M, Kowalski KG, Cole S, Kerwash E, Wade JR, Liu C, Wang Y, Trame MN, Zhu H, Wilkins JJ; ISoP Standards & Best Practices Committee. Sanghavi K, et al. Among authors: wade jr. CPT Pharmacometrics Syst Pharmacol. 2024 Apr 2. doi: 10.1002/psp4.13115. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38566433 Free article. Review.
1,669 results