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Re-structuring lentiviral vectors to express genomic RNA via cap-dependent translation.
Counsell JR, De Brabandere G, Karda R, Moore M, Greco A, Bray A, Diaz JA, Perocheau DP, Mock U, Waddington SN. Counsell JR, et al. Among authors: waddington sn. Mol Ther Methods Clin Dev. 2020 Dec 15;20:357-365. doi: 10.1016/j.omtm.2020.12.005. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2020. PMID: 33553484 Free PMC article.
Stable gene transfer to muscle using non-integrating lentiviral vectors.
Apolonia L, Waddington SN, Fernandes C, Ward NJ, Bouma G, Blundell MP, Thrasher AJ, Collins MK, Philpott NJ. Apolonia L, et al. Among authors: waddington sn. Mol Ther. 2007 Nov;15(11):1947-54. doi: 10.1038/sj.mt.6300281. Epub 2007 Aug 14. Mol Ther. 2007. PMID: 17700544 Free article.
Perinatal systemic gene delivery using adeno-associated viral vectors.
Karda R, Buckley SM, Mattar CN, Ng J, Massaro G, Hughes MP, Kurian MA, Baruteau J, Gissen P, Chan JK, Bacchelli C, Waddington SN, Rahim AA. Karda R, et al. Among authors: waddington sn. Front Mol Neurosci. 2014 Nov 14;7:89. doi: 10.3389/fnmol.2014.00089. eCollection 2014. Front Mol Neurosci. 2014. PMID: 25452713 Free PMC article. Review.
Gene Therapy with Adeno-associated Virus for Cystic Fibrosis.
Karda R, Buckley SM, Waddington SN. Karda R, et al. Among authors: waddington sn. Am J Respir Crit Care Med. 2016 Feb 1;193(3):234-6. doi: 10.1164/rccm.201510-2024ED. Am J Respir Crit Care Med. 2016. PMID: 26829420 No abstract available.
Lentiviral vectors can be used for full-length dystrophin gene therapy.
Counsell JR, Asgarian Z, Meng J, Ferrer V, Vink CA, Howe SJ, Waddington SN, Thrasher AJ, Muntoni F, Morgan JE, Danos O. Counsell JR, et al. Among authors: waddington sn. Sci Rep. 2017 Mar 6;7(1):79. doi: 10.1038/s41598-017-00152-5. Sci Rep. 2017. PMID: 28250438 Free PMC article.
168 results