Waddell MB - Search Results

1

Architecture of the bacteriophage T4 activator MotA/promoter DNA interaction during sigma appropriation.

Hsieh ML, James TD, Knipling L, Waddell MB, White S, Hinton DM. Hsieh ML, et al. Among authors: waddell mb. J Biol Chem. 2013 Sep 20;288(38):27607-27618. doi: 10.1074/jbc.M113.475434. Epub 2013 Jul 31. J Biol Chem. 2013. PMID: 23902794 Free PMC article.

2

The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA.

Cuypers MG, Robertson RM, Knipling L, Waddell MB, Moon K, Hinton DM, White SW. Cuypers MG, et al. Among authors: waddell mb. Nucleic Acids Res. 2018 Jun 1;46(10):5308-5318. doi: 10.1093/nar/gky292. Nucleic Acids Res. 2018. PMID: 29718457 Free PMC article.

3

Structure and mechanism of the phage T4 recombination mediator protein UvsY.

Gajewski S, Waddell MB, Vaithiyalingam S, Nourse A, Li Z, Woetzel N, Alexander N, Meiler J, White SW. Gajewski S, et al. Among authors: waddell mb. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3275-80. doi: 10.1073/pnas.1519154113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951671 Free PMC article.

4

Catalysis and sulfa drug resistance in dihydropteroate synthase.

Yun MK, Wu Y, Li Z, Zhao Y, Waddell MB, Ferreira AM, Lee RE, Bashford D, White SW. Yun MK, et al. Among authors: waddell mb. Science. 2012 Mar 2;335(6072):1110-4. doi: 10.1126/science.1214641. Science. 2012. PMID: 22383850 Free PMC article.

5

The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

Yun MK, Hoagland D, Kumar G, Waddell MB, Rock CO, Lee RE, White SW. Yun MK, et al. Among authors: waddell mb. Bioorg Med Chem. 2014 Apr 1;22(7):2157-65. doi: 10.1016/j.bmc.2014.02.022. Epub 2014 Feb 25. Bioorg Med Chem. 2014. PMID: 24613625 Free PMC article.

6

Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer.

Slavish PJ, Chi L, Yun MK, Tsurkan L, Martinez NE, Jonchere B, Chai SC, Connelly M, Waddell MB, Das S, Neale G, Li Z, Shadrick WR, Olsen RR, Freeman KW, Low JA, Price JE, Young BM, Bharatham N, Boyd VA, Yang J, Lee RE, Morfouace M, Roussel MF, Chen T, Savic D, Guy RK, White SW, Shelat AA, Potter PM. Slavish PJ, et al. Among authors: waddell mb. Cancer Res. 2020 Sep 1;80(17):3507-3518. doi: 10.1158/0008-5472.CAN-19-3934. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651255 Free PMC article.

7

Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.

Tsytlonok M, Sanabria H, Wang Y, Felekyan S, Hemmen K, Phillips AH, Yun MK, Waddell MB, Park CG, Vaithiyalingam S, Iconaru L, White SW, Tompa P, Seidel CAM, Kriwacki R. Tsytlonok M, et al. Among authors: waddell mb. Nat Commun. 2019 Apr 11;10(1):1676. doi: 10.1038/s41467-019-09446-w. Nat Commun. 2019. PMID: 30976006 Free PMC article.

8

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.

Zhuang M, Calabrese MF, Liu J, Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA. Zhuang M, et al. Among authors: waddell mb. Mol Cell. 2009 Oct 9;36(1):39-50. doi: 10.1016/j.molcel.2009.09.022. Mol Cell. 2009. PMID: 19818708 Free PMC article.

9

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.

Huang DT, Paydar A, Zhuang M, Waddell MB, Holton JM, Schulman BA. Huang DT, et al. Among authors: waddell mb. Mol Cell. 2005 Feb 4;17(3):341-50. doi: 10.1016/j.molcel.2004.12.020. Mol Cell. 2005. PMID: 15694336 Free article.

10

Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.

Souphron J, Waddell MB, Paydar A, Tokgöz-Gromley Z, Roussel MF, Schulman BA. Souphron J, et al. Among authors: waddell mb. Biochemistry. 2008 Aug 26;47(34):8961-9. doi: 10.1021/bi800604c. Epub 2008 Jul 25. Biochemistry. 2008. PMID: 18652489 Free PMC article.

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