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Page 1
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig S, Merbach AK, Kniffka JA, Antes M, Szu-Tu C, Rohde C, Waclawiczek A, Stelmach P, Gräßle S, Pervan P, Janssen M, Landry JJM, Benes V, Jauch A, Brough M, Bauer M, Besenbeck B, Felden J, Bäumer S, Hundemer M, Sauer T, Pabst C, Wickenhauser C, Angenendt L, Schliemann C, Trumpp A, Haas S, Scherer M, Raffel S, Müller-Tidow C, Velten L. Beneyto-Calabuig S, et al. Among authors: waclawiczek a. Cell Stem Cell. 2023 May 4;30(5):706-721.e8. doi: 10.1016/j.stem.2023.04.001. Epub 2023 Apr 24. Cell Stem Cell. 2023. PMID: 37098346 Free article.
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1.
Janssen M, Schmidt C, Bruch PM, Blank MF, Rohde C, Waclawiczek A, Heid D, Renders S, Göllner S, Vierbaum L, Besenbeck B, Herbst SA, Knoll M, Kolb C, Przybylla A, Weidenauer K, Ludwig AK, Fabre M, Gu M, Schlenk RF, Stölzel F, Bornhäuser M, Röllig C, Platzbecker U, Baldus C, Serve H, Sauer T, Raffel S, Pabst C, Vassiliou G, Vick B, Jeremias I, Trumpp A, Krijgsveld J, Müller-Tidow C, Dietrich S. Janssen M, et al. Among authors: waclawiczek a. Blood. 2022 Dec 15;140(24):2594-2610. doi: 10.1182/blood.2021014241. Blood. 2022. PMID: 35857899 Free article.
Protein tyrosine kinase 2b inhibition reverts niche-associated resistance to tyrosine kinase inhibitors in AML.
Allert C, Waclawiczek A, Zimmermann SMN, Göllner S, Heid D, Janssen M, Renders S, Rohde C, Bauer M, Bruckmann M, Zinz R, Pauli C, Besenbeck B, Wickenhauser C, Trumpp A, Krijgsveld J, Müller-Tidow C, Blank MF. Allert C, et al. Among authors: waclawiczek a. Leukemia. 2022 Oct;36(10):2418-2429. doi: 10.1038/s41375-022-01687-x. Epub 2022 Sep 2. Leukemia. 2022. PMID: 36056084 Free PMC article.
Combinatorial BCL2 Family Expression in Acute Myeloid Leukemia Stem Cells Predicts Clinical Response to Azacitidine/Venetoclax.
Waclawiczek A, Leppä AM, Renders S, Stumpf K, Reyneri C, Betz B, Janssen M, Shahswar R, Donato E, Karpova D, Thiel V, Unglaub JM, Grabowski S, Gryzik S, Vierbaum L, Schlenk RF, Röllig C, Hundemer M, Pabst C, Heuser M, Raffel S, Müller-Tidow C, Sauer T, Trumpp A. Waclawiczek A, et al. Cancer Discov. 2023 Jun 2;13(6):1408-1427. doi: 10.1158/2159-8290.CD-22-0939. Cancer Discov. 2023. PMID: 36892565 Free PMC article.
The ribosomal protein S6 kinase alpha-1 (RPS6KA1) induces resistance to venetoclax/azacitidine in acute myeloid leukemia.
Weidenauer K, Schmidt C, Rohde C, Pauli C, Blank MF, Heid D, Waclawiczek A, Corbacioglu A, Göllner S, Lotze M, Vierbaum L, Renders S, Krijgsveld J, Raffel S, Sauer T, Trumpp A, Pabst C, Müller-Tidow C, Janssen M. Weidenauer K, et al. Among authors: waclawiczek a. Leukemia. 2023 Aug;37(8):1611-1625. doi: 10.1038/s41375-023-01951-8. Epub 2023 Jul 6. Leukemia. 2023. PMID: 37414921 Free PMC article.
Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.
Passaro D, Garcia-Albornoz M, Diana G, Chakravarty P, Ariza-McNaughton L, Batsivari A, Borràs-Eroles C, Abarrategi A, Waclawiczek A, Ombrato L, Malanchi I, Gribben J, Bonnet D. Passaro D, et al. Among authors: waclawiczek a. Cell Rep. 2021 May 11;35(6):109119. doi: 10.1016/j.celrep.2021.109119. Cell Rep. 2021. PMID: 33979628 Free PMC article.
The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions.
Marschallinger J, Sah A, Schmuckermair C, Unger M, Rotheneichner P, Kharitonova M, Waclawiczek A, Gerner P, Jaksch-Bogensperger H, Berger S, Striessnig J, Singewald N, Couillard-Despres S, Aigner L. Marschallinger J, et al. Among authors: waclawiczek a. Cell Calcium. 2015 Dec;58(6):606-16. doi: 10.1016/j.ceca.2015.09.007. Epub 2015 Oct 3. Cell Calcium. 2015. PMID: 26459417
Generation of neighbor-labeling cells to study intercellular interactions in vivo.
Ombrato L, Nolan E, Passaro D, Kurelac I, Bridgeman VL, Waclawiczek A, Duarte D, Lo Celso C, Bonnet D, Malanchi I. Ombrato L, et al. Among authors: waclawiczek a. Nat Protoc. 2021 Feb;16(2):872-892. doi: 10.1038/s41596-020-00438-5. Epub 2020 Dec 11. Nat Protoc. 2021. PMID: 33311715 Free PMC article.
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