Wack A - Search Results

1

The interferon landscape along the respiratory tract impacts the severity of COVID-19.

Sposito B, Broggi A, Pandolfi L, Crotta S, Clementi N, Ferrarese R, Sisti S, Criscuolo E, Spreafico R, Long JM, Ambrosi A, Liu E, Frangipane V, Saracino L, Bozzini S, Marongiu L, Facchini FA, Bottazzi A, Fossali T, Colombo R, Clementi M, Tagliabue E, Chou J, Pontiroli AE, Meloni F, Wack A, Mancini N, Zanoni I. Sposito B, et al. Among authors: wack a. Cell. 2021 Sep 16;184(19):4953-4968.e16. doi: 10.1016/j.cell.2021.08.016. Epub 2021 Aug 19. Cell. 2021. PMID: 34492226 Free PMC article.

2

Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection.

Crotta S, Brazzoli M, Piccioli D, Valiante NM, Wack A. Crotta S, et al. Among authors: wack a. J Hepatol. 2010 Feb;52(2):183-90. doi: 10.1016/j.jhep.2009.11.003. Epub 2009 Dec 16. J Hepatol. 2010. PMID: 20015567

3

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.

Crotta S, Davidson S, Mahlakoiv T, Desmet CJ, Buckwalter MR, Albert ML, Staeheli P, Wack A. Crotta S, et al. Among authors: wack a. PLoS Pathog. 2013;9(11):e1003773. doi: 10.1371/journal.ppat.1003773. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278020 Free PMC article.

4

Pathogenic potential of interferon αβ in acute influenza infection.

Davidson S, Crotta S, McCabe TM, Wack A. Davidson S, et al. Among authors: wack a. Nat Commun. 2014 May 21;5:3864. doi: 10.1038/ncomms4864. Nat Commun. 2014. PMID: 24844667 Free PMC article.

5

A serpin shapes the extracellular environment to prevent influenza A virus maturation.

Dittmann M, Hoffmann HH, Scull MA, Gilmore RH, Bell KL, Ciancanelli M, Wilson SJ, Crotta S, Yu Y, Flatley B, Xiao JW, Casanova JL, Wack A, Bieniasz PD, Rice CM. Dittmann M, et al. Among authors: wack a. Cell. 2015 Feb 12;160(4):631-643. doi: 10.1016/j.cell.2015.01.040. Cell. 2015. PMID: 25679759 Free PMC article.

6

TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection.

Ellis GT, Davidson S, Crotta S, Branzk N, Papayannopoulos V, Wack A. Ellis GT, et al. Among authors: wack a. EMBO Rep. 2015 Sep;16(9):1203-18. doi: 10.15252/embr.201540473. Epub 2015 Aug 11. EMBO Rep. 2015. PMID: 26265006 Free PMC article.

7

IFNλ is a potent anti-influenza therapeutic without the inflammatory side effects of IFNα treatment.

Davidson S, McCabe TM, Crotta S, Gad HH, Hessel EM, Beinke S, Hartmann R, Wack A. Davidson S, et al. Among authors: wack a. EMBO Mol Med. 2016 Sep 1;8(9):1099-112. doi: 10.15252/emmm.201606413. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27520969 Free PMC article.

8

Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection.

Bradley KC, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, Fuchs SY, Staeheli P, Wack A. Bradley KC, et al. Among authors: wack a. Cell Rep. 2019 Jul 2;28(1):245-256.e4. doi: 10.1016/j.celrep.2019.05.105. Cell Rep. 2019. PMID: 31269444 Free article.

9

Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection.

Aegerter H, Kulikauskaite J, Crotta S, Patel H, Kelly G, Hessel EM, Mack M, Beinke S, Wack A. Aegerter H, et al. Among authors: wack a. Nat Immunol. 2020 Feb;21(2):145-157. doi: 10.1038/s41590-019-0568-x. Epub 2020 Jan 13. Nat Immunol. 2020. PMID: 31932810 Free PMC article.

10

COVID-19 and emerging viral infections: The case for interferon lambda.

Prokunina-Olsson L, Alphonse N, Dickenson RE, Durbin JE, Glenn JS, Hartmann R, Kotenko SV, Lazear HM, O'Brien TR, Odendall C, Onabajo OO, Piontkivska H, Santer DM, Reich NC, Wack A, Zanoni I. Prokunina-Olsson L, et al. Among authors: wack a. J Exp Med. 2020 May 4;217(5):e20200653. doi: 10.1084/jem.20200653. J Exp Med. 2020. PMID: 32289152 Free PMC article.

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