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Maintaining proteostasis under mechanical stress.
Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B. Höhfeld J, et al. Among authors: wachten d. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507. Epub 2021 Jul 26. EMBO Rep. 2021. PMID: 34309183 Free PMC article. Review.
Direct action of endocrine disrupting chemicals on human sperm.
Schiffer C, Müller A, Egeberg DL, Alvarez L, Brenker C, Rehfeld A, Frederiksen H, Wäschle B, Kaupp UB, Balbach M, Wachten D, Skakkebaek NE, Almstrup K, Strünker T. Schiffer C, et al. Among authors: wachten d. EMBO Rep. 2014 Jul;15(7):758-65. doi: 10.15252/embr.201438869. Epub 2014 May 12. EMBO Rep. 2014. PMID: 24820036 Free PMC article.
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation.
Hansen JN, Kaiser F, Leyendecker P, Stüven B, Krause JH, Derakhshandeh F, Irfan J, Sroka TJ, Preval KM, Desai PB, Kraut M, Theis H, Drews AD, De-Domenico E, Händler K, Pazour GJ, Henderson DJP, Mick DU, Wachten D. Hansen JN, et al. Among authors: wachten d. EMBO Rep. 2022 Aug 3;23(8):e54315. doi: 10.15252/embr.202154315. Epub 2022 Jun 13. EMBO Rep. 2022. PMID: 35695071 Free PMC article.
Emerging principles of primary cilia dynamics in controlling tissue organization and function.
Gopalakrishnan J, Feistel K, Friedrich BM, Grapin-Botton A, Jurisch-Yaksi N, Mass E, Mick DU, Müller RU, May-Simera H, Schermer B, Schmidts M, Walentek P, Wachten D. Gopalakrishnan J, et al. Among authors: wachten d. EMBO J. 2023 Nov 2;42(21):e113891. doi: 10.15252/embj.2023113891. Epub 2023 Sep 25. EMBO J. 2023. PMID: 37743763 Free PMC article. Review.
CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending.
Krähling AM, Alvarez L, Debowski K, Van Q, Gunkel M, Irsen S, Al-Amoudi A, Strünker T, Kremmer E, Krause E, Voigt I, Wörtge S, Waisman A, Weyand I, Seifert R, Kaupp UB, Wachten D. Krähling AM, et al. Among authors: wachten d. PLoS Genet. 2013;9(12):e1003960. doi: 10.1371/journal.pgen.1003960. Epub 2013 Dec 5. PLoS Genet. 2013. PMID: 24339785 Free PMC article.
Targeted inactivation of the mouse epididymal beta-defensin 41 alters sperm flagellar beat pattern and zona pellucida binding.
Björkgren I, Alvarez L, Blank N, Balbach M, Turunen H, Laajala TD, Toivanen J, Krutskikh A, Wahlberg N, Huhtaniemi I, Poutanen M, Wachten D, Sipilä P. Björkgren I, et al. Among authors: wachten d. Mol Cell Endocrinol. 2016 May 15;427:143-54. doi: 10.1016/j.mce.2016.03.013. Epub 2016 Mar 14. Mol Cell Endocrinol. 2016. PMID: 26987518
A novel biosensor to study cAMP dynamics in cilia and flagella.
Mukherjee S, Jansen V, Jikeli JF, Hamzeh H, Alvarez L, Dombrowski M, Balbach M, Strünker T, Seifert R, Kaupp UB, Wachten D. Mukherjee S, et al. Among authors: wachten d. Elife. 2016 Mar 22;5:e14052. doi: 10.7554/eLife.14052. Elife. 2016. PMID: 27003291 Free PMC article.
60 results