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Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations.
Woeste MA, Stern S, Raju DN, Grahn E, Dittmann D, Gutbrod K, Dörmann P, Hansen JN, Schonauer S, Marx CE, Hamzeh H, Körschen HG, Aerts JMFG, Bönigk W, Endepols H, Sandhoff R, Geyer M, Berger TK, Bradke F, Wachten D. Woeste MA, et al. Among authors: wachten d. J Biol Chem. 2019 Mar 15;294(11):3853-3871. doi: 10.1074/jbc.RA118.006311. Epub 2019 Jan 20. J Biol Chem. 2019. PMID: 30662006 Free PMC article.
1-O-acylceramides are natural components of human and mouse epidermis.
Rabionet M, Bayerle A, Marsching C, Jennemann R, Gröne HJ, Yildiz Y, Wachten D, Shaw W, Shayman JA, Sandhoff R. Rabionet M, et al. Among authors: wachten d. J Lipid Res. 2013 Dec;54(12):3312-21. doi: 10.1194/jlr.M040097. Epub 2013 Sep 27. J Lipid Res. 2013. PMID: 24078707 Free PMC article.
A novel biosensor to study cAMP dynamics in cilia and flagella.
Mukherjee S, Jansen V, Jikeli JF, Hamzeh H, Alvarez L, Dombrowski M, Balbach M, Strünker T, Seifert R, Kaupp UB, Wachten D. Mukherjee S, et al. Among authors: wachten d. Elife. 2016 Mar 22;5:e14052. doi: 10.7554/eLife.14052. Elife. 2016. PMID: 27003291 Free PMC article.
Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.
Schonauer S, Körschen HG, Penno A, Rennhack A, Breiden B, Sandhoff K, Gutbrod K, Dörmann P, Raju DN, Haberkant P, Gerl MJ, Brügger B, Zigdon H, Vardi A, Futerman AH, Thiele C, Wachten D. Schonauer S, et al. Among authors: wachten d. J Biol Chem. 2017 Apr 14;292(15):6177-6189. doi: 10.1074/jbc.M116.762831. Epub 2017 Mar 3. J Biol Chem. 2017. PMID: 28258214 Free PMC article.
Shedding light on the role of cAMP in mammalian sperm physiology.
Balbach M, Beckert V, Hansen JN, Wachten D. Balbach M, et al. Among authors: wachten d. Mol Cell Endocrinol. 2018 Jun 15;468:111-120. doi: 10.1016/j.mce.2017.11.008. Epub 2017 Nov 13. Mol Cell Endocrinol. 2018. PMID: 29146556 Review.
The Enigmatic Role of GBA2 in Controlling Locomotor Function.
Woeste MA, Wachten D. Woeste MA, et al. Among authors: wachten d. Front Mol Neurosci. 2017 Nov 28;10:386. doi: 10.3389/fnmol.2017.00386. eCollection 2017. Front Mol Neurosci. 2017. PMID: 29234271 Free PMC article. Review.
61 results