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Metformin treatment rescues CD8+ T-cell response to immune checkpoint inhibitor therapy in mice with NAFLD.
Wabitsch S, McCallen JD, Kamenyeva O, Ruf B, McVey JC, Kabat J, Walz JS, Rotman Y, Bauer KC, Craig AJ, Pouzolles M, Phadke I, Catania V, Green BL, Fu C, Diggs LP, Heinrich B, Wang XW, Ma C, Greten TF. Wabitsch S, et al. J Hepatol. 2022 Sep;77(3):748-760. doi: 10.1016/j.jhep.2022.03.010. Epub 2022 Apr 1. J Hepatol. 2022. PMID: 35378172 Free PMC article.
Steatohepatitis Impairs T-cell-Directed Immunotherapies Against Liver Tumors in Mice.
Heinrich B, Brown ZJ, Diggs LP, Vormehr M, Ma C, Subramanyam V, Rosato U, Ruf B, Walz JS, McVey JC, Wabitsch S, Fu Q, Yu SJ, Zhang Q, Lai CW, Sahin U, Greten TF. Heinrich B, et al. Among authors: wabitsch s. Gastroenterology. 2021 Jan;160(1):331-345.e6. doi: 10.1053/j.gastro.2020.09.031. Epub 2020 Oct 1. Gastroenterology. 2021. PMID: 33010248 Free PMC article.
CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma.
Diggs LP, Ruf B, Ma C, Heinrich B, Cui L, Zhang Q, McVey JC, Wabitsch S, Heinrich S, Rosato U, Lai W, Subramanyam V, Longerich T, Loosen SH, Luedde T, Neumann UP, Desar S, Kleiner D, Gores G, Wang XW, Greten TF. Diggs LP, et al. Among authors: wabitsch s. J Hepatol. 2021 May;74(5):1145-1154. doi: 10.1016/j.jhep.2020.11.037. Epub 2020 Dec 1. J Hepatol. 2021. PMID: 33276030 Free PMC article.
Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma.
Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TF. Zhang Q, et al. Among authors: wabitsch s. Cancer Discov. 2021 May;11(5):1248-1267. doi: 10.1158/2159-8290.CD-20-0304. Epub 2020 Dec 15. Cancer Discov. 2021. PMID: 33323397 Free PMC article.
Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response.
Ruf B, Catania VV, Wabitsch S, Ma C, Diggs LP, Zhang Q, Heinrich B, Subramanyam V, Cui LL, Pouzolles M, Evans CN, Chari R, Sakai S, Oh S, Barry CE 3rd, Barber DL, Greten TF. Ruf B, et al. Among authors: wabitsch s. Cancer Immunol Res. 2021 Sep;9(9):1024-1034. doi: 10.1158/2326-6066.CIR-20-0925. Epub 2021 Jun 30. Cancer Immunol Res. 2021. PMID: 34193462 Free PMC article.
Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD.
Ma C, Fu Q, Diggs LP, McVey JC, McCallen J, Wabitsch S, Ruf B, Brown Z, Heinrich B, Zhang Q, Rosato U, Wang S, Cui L, Berzofsky JA, Kleiner DE, Bosco DB, Wu LJ, Lai CW, Rotman Y, Xie C, Korangy F, Greten TF. Ma C, et al. Among authors: wabitsch s. Cancer Cell. 2022 Sep 12;40(9):986-998.e5. doi: 10.1016/j.ccell.2022.08.004. Epub 2022 Sep 1. Cancer Cell. 2022. PMID: 36055226 Free PMC article.
31 results