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Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene Loss.
Suárez NM, Wilkie GS, Hage E, Camiolo S, Holton M, Hughes J, Maabar M, Vattipally SB, Dhingra A, Gompels UA, Wilkinson GWG, Baldanti F, Furione M, Lilleri D, Arossa A, Ganzenmueller T, Gerna G, Hubáček P, Schulz TF, Wolf D, Zavattoni M, Davison AJ. Suárez NM, et al. J Infect Dis. 2019 Jul 31;220(5):781-791. doi: 10.1093/infdis/jiz208. J Infect Dis. 2019. PMID: 31050742 Free PMC article.
Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.
Wang ECY, Pjechova M, Nightingale K, Vlahava VM, Patel M, Ruckova E, Forbes SK, Nobre L, Antrobus R, Roberts D, Fielding CA, Seirafian S, Davies J, Murrell I, Lau B, Wilkie GS, Suárez NM, Stanton RJ, Vojtesek B, Davison A, Lehner PJ, Weekes MP, Wilkinson GWG, Tomasec P. Wang ECY, et al. Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24. Proc Natl Acad Sci U S A. 2018. PMID: 29691324 Free PMC article.
Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation.
Fielding CA, Weekes MP, Nobre LV, Ruckova E, Wilkie GS, Paulo JA, Chang C, Suárez NM, Davies JA, Antrobus R, Stanton RJ, Aicheler RJ, Nichols H, Vojtesek B, Trowsdale J, Davison AJ, Gygi SP, Tomasec P, Lehner PJ, Wilkinson GW. Fielding CA, et al. Elife. 2017 Feb 10;6:e22206. doi: 10.7554/eLife.22206. Elife. 2017. PMID: 28186488 Free PMC article.
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.
Stanton RJ, Prod'homme V, Purbhoo MA, Moore M, Aicheler RJ, Heinzmann M, Bailer SM, Haas J, Antrobus R, Weekes MP, Lehner PJ, Vojtesek B, Miners KL, Man S, Wilkie GS, Davison AJ, Wang ECY, Tomasec P, Wilkinson GWG. Stanton RJ, et al. Cell Host Microbe. 2014 Aug 13;16(2):201-214. doi: 10.1016/j.chom.2014.07.005. Cell Host Microbe. 2014. PMID: 25121749 Free PMC article.
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation.
Fielding CA, Aicheler R, Stanton RJ, Wang EC, Han S, Seirafian S, Davies J, McSharry BP, Weekes MP, Antrobus PR, Prod'homme V, Blanchet FP, Sugrue D, Cuff S, Roberts D, Davison AJ, Lehner PJ, Wilkinson GW, Tomasec P. Fielding CA, et al. PLoS Pathog. 2014 May 1;10(5):e1004058. doi: 10.1371/journal.ppat.1004058. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24787765 Free PMC article.
Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.
Stacey MA, Marsden M, Pham N TA, Clare S, Dolton G, Stack G, Jones E, Klenerman P, Gallimore AM, Taylor PR, Snelgrove RJ, Lawley TD, Dougan G, Benedict CA, Jones SA, Wilkinson GW, Humphreys IR. Stacey MA, et al. Cell Host Microbe. 2014 Apr 9;15(4):471-83. doi: 10.1016/j.chom.2014.03.003. Cell Host Microbe. 2014. PMID: 24721575 Free PMC article.
Human cytomegalovirus suppresses Fas expression and function.
Seirafian S, Prod'homme V, Sugrue D, Davies J, Fielding C, Tomasec P, Wilkinson GWG. Seirafian S, et al. J Gen Virol. 2014 Apr;95(Pt 4):933-939. doi: 10.1099/vir.0.058313-0. Epub 2014 Jan 6. J Gen Virol. 2014. PMID: 24394698 Free PMC article.