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Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.
J Med Chem. 2024 Apr 25;67(8):6495-6507. doi: 10.1021/acs.jmedchem.3c02416. Epub 2024 Apr 12.
J Med Chem. 2024.
PMID: 38608245
Free PMC article.
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors.
Khatua K, Alugubelli YR, Yang KS, Vulupala VR, Blankenship LR, Coleman D, Atla S, Chaki SP, Geng ZZ, Ma XR, Xiao J, Chen PH, Cho CD, Sharma S, Vatansever EC, Ma Y, Yu G, Neuman BW, Xu S, Liu WR.
Khatua K, et al. Among authors: vulupala vr.
Antiviral Res. 2024 May;225:105874. doi: 10.1016/j.antiviral.2024.105874. Epub 2024 Mar 28.
Antiviral Res. 2024.
PMID: 38555023
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Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.
Alugubelli YR, Xiao J, Khatua K, Kumar S, Ma Y, Ma XR, Vulupala VR, Atla SR, Blankenship L, Coleman D, Neuman BW, Liu WR, Xu S.
Alugubelli YR, et al. Among authors: vulupala vr.
bioRxiv [Preprint]. 2023 Sep 29:2023.09.29.560163. doi: 10.1101/2023.09.29.560163.
bioRxiv. 2023.
PMID: 37808777
Free PMC article.
Updated.
Preprint.
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An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease.
Khatua K, Alugubelli YR, Yang KS, Vulupala VR, Blankenship LR, Coleman DD, Atla S, Chaki SP, Geng ZZ, Ma XR, Xiao J, Chen PC, Cho CD, Vatansever EC, Ma Y, Yu G, Neuman BW, Xu S, Liu WR.
Khatua K, et al. Among authors: vulupala vr.
bioRxiv [Preprint]. 2023 Apr 12:2023.04.11.536467. doi: 10.1101/2023.04.11.536467.
bioRxiv. 2023.
PMID: 37090597
Free PMC article.
Preprint.
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A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease.
Geng ZZ, Atla S, Shaabani N, Vulupala VR, Yang KS, Alugubelli YR, Khatua K, Chen PC, Xiao J, Blankenship LR, Ma XR, Vatansever EC, Cho CC, Ma Y, Allen R, Ji H, Xu S, Liu WR.
Geng ZZ, et al. Among authors: vulupala vr.
bioRxiv [Preprint]. 2023 Jan 18:2023.01.17.524469. doi: 10.1101/2023.01.17.524469.
bioRxiv. 2023.
PMID: 36711580
Free PMC article.
Updated.
Preprint.
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