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Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients.
Davar D, Dzutsev AK, McCulloch JA, Rodrigues RR, Chauvin JM, Morrison RM, Deblasio RN, Menna C, Ding Q, Pagliano O, Zidi B, Zhang S, Badger JH, Vetizou M, Cole AM, Fernandes MR, Prescott S, Costa RGF, Balaji AK, Morgun A, Vujkovic-Cvijin I, Wang H, Borhani AA, Schwartz MB, Dubner HM, Ernst SJ, Rose A, Najjar YG, Belkaid Y, Kirkwood JM, Trinchieri G, Zarour HM. Davar D, et al. Among authors: vujkovic cvijin i. Science. 2021 Feb 5;371(6529):595-602. doi: 10.1126/science.abf3363. Science. 2021. PMID: 33542131 Free PMC article. Clinical Trial.
Linking the Microbiota, Chronic Disease, and the Immune System.
Hand TW, Vujkovic-Cvijin I, Ridaura VK, Belkaid Y. Hand TW, et al. Trends Endocrinol Metab. 2016 Dec;27(12):831-843. doi: 10.1016/j.tem.2016.08.003. Epub 2016 Sep 10. Trends Endocrinol Metab. 2016. PMID: 27623245 Free PMC article. Review.
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.
Linehan JL, Harrison OJ, Han SJ, Byrd AL, Vujkovic-Cvijin I, Villarino AV, Sen SK, Shaik J, Smelkinson M, Tamoutounour S, Collins N, Bouladoux N, Dzutsev A, Rosshart SP, Arbuckle JH, Wang CR, Kristie TM, Rehermann B, Trinchieri G, Brenchley JM, O'Shea JJ, Belkaid Y. Linehan JL, et al. Cell. 2018 Feb 8;172(4):784-796.e18. doi: 10.1016/j.cell.2017.12.033. Epub 2018 Jan 18. Cell. 2018. PMID: 29358051 Free PMC article.
MAIT cells are imprinted by the microbiota in early life and promote tissue repair.
Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, Roy S, Cua DJ, Adams EJ, Bhandoola A, Scharschmidt TC, Aubé J, Fischbach MA, Belkaid Y. Constantinides MG, et al. Science. 2019 Oct 25;366(6464):eaax6624. doi: 10.1126/science.aax6624. Science. 2019. PMID: 31649166 Free PMC article.
Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses.
Tamoutounour S, Han SJ, Deckers J, Constantinides MG, Hurabielle C, Harrison OJ, Bouladoux N, Linehan JL, Link VM, Vujkovic-Cvijin I, Perez-Chaparro PJ, Rosshart SP, Rehermann B, Lazarevic V, Belkaid Y. Tamoutounour S, et al. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23643-23652. doi: 10.1073/pnas.1912432116. Epub 2019 Oct 31. Proc Natl Acad Sci U S A. 2019. PMID: 31672911 Free PMC article.
Host variables confound gut microbiota studies of human disease.
Vujkovic-Cvijin I, Sklar J, Jiang L, Natarajan L, Knight R, Belkaid Y. Vujkovic-Cvijin I, et al. Nature. 2020 Nov;587(7834):448-454. doi: 10.1038/s41586-020-2881-9. Epub 2020 Nov 4. Nature. 2020. PMID: 33149306 Free PMC article.
31 results