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Structure-Activity Relationships of Truncated 1'-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs.
Hyun YE, An S, Kim M, Park IG, Yoon S, Javaid HMA, Vu TNL, Kim G, Choi H, Lee HW, Noh M, Huh JY, Choi S, Kim HR, Jeong LS. Hyun YE, et al. Among authors: vu tnl. J Med Chem. 2023 Apr 13;66(7):4961-4978. doi: 10.1021/acs.jmedchem.2c02071. Epub 2023 Mar 26. J Med Chem. 2023. PMID: 36967575
Discovery of (E)-3-(3-((2-Cyano-4'-dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis.
Shim S, Krishnaiah M, Sankham MR, Kim I, Lee Y, Shin I, Oh AR, Lee HJ, Vu TNL, Park J, Choi S, Park S, Kwon Y, Fang S, Kim DK. Shim S, et al. Among authors: vu tnl. J Med Chem. 2022 Jul 28;65(14):9974-10000. doi: 10.1021/acs.jmedchem.2c00641. Epub 2022 Jul 7. J Med Chem. 2022. PMID: 35797110
2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists.
Kang JM, Kwon SO, Ann J, Lee S, Kim C, Do N, Jeong JJ, Blumberg PM, Ha H, Vu TNL, Yoon S, Choi S, Frank-Foltyn R, Lesch B, Bahrenberg G, Stockhausen H, Christoph T, Lee J. Kang JM, et al. Among authors: vu tnl. Bioorg Med Chem Lett. 2021 Sep 15;48:128266. doi: 10.1016/j.bmcl.2021.128266. Epub 2021 Jul 14. Bioorg Med Chem Lett. 2021. PMID: 34273488