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Page 1
PROTAC-mediated crosstalk between E3 ligases.
Steinebach C , Kehm H , Lindner S , Vu LP , Köpff S , López Mármol Á , Weiler C , Wagner KG , Reichenzeller M , Krönke J , Gütschow M . Steinebach C , et al. Among authors: vu lp. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824. doi: 10.1039/c8cc09541h. Chem Commun (Camb). 2019. PMID: 30672516
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders.
Steinebach C, Ng YLD, Sosič I, Lee CS, Chen S, Lindner S, Vu LP, Bricelj A, Haschemi R, Monschke M, Steinwarz E, Wagner KG, Bendas G, Luo J, Gütschow M, Krönke J. Steinebach C, et al. Among authors: vu lp. Chem Sci. 2020 Mar 4;11(13):3474-3486. doi: 10.1039/d0sc00167h. eCollection 2020 Apr 7. Chem Sci. 2020. PMID: 33133483 Free PMC article.
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers.
Vu LP, Diehl CJ, Casement R, Bond AG, Steinebach C, Strašek N, Bricelj A, Perdih A, Schnakenburg G, Sosič I, Ciulli A, Gütschow M. Vu LP, et al. J Med Chem. 2023 Sep 28;66(18):12776-12811. doi: 10.1021/acs.jmedchem.3c00434. Epub 2023 Sep 14. J Med Chem. 2023. PMID: 37708384 Free PMC article.
mRNA-based therapeutic strategies for cancer treatment.
Taibi T, Cheon S, Perna F, Vu LP. Taibi T, et al. Among authors: vu lp. Mol Ther. 2024 May 2:S1525-0016(24)00299-5. doi: 10.1016/j.ymthe.2024.04.035. Online ahead of print. Mol Ther. 2024. PMID: 38702886 Review.
Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis.
Ghashghaei M, Liu Y, Ettles J, Bombaci G, Ramkumar N, Liu Z, Escano L, Miko SS, Kim Y, Waldron JA, Do K, MacPherson K, Yuen KA, Taibi T, Yue M, Arsalan A, Jin Z, Edin G, Karsan A, Morin GB, Kuchenbauer F, Perna F, Bushell M, Vu LP. Ghashghaei M, et al. Among authors: vu lp. Nat Commun. 2024 Mar 15;15(1):2340. doi: 10.1038/s41467-024-46665-2. Nat Commun. 2024. PMID: 38491013 Free PMC article.
A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma.
Di Meo F, Iyer A, Akama K, Cheng R, Yu C, Cesarano A, Kurihara N, Tenshin H, Aljoufi A, Marino S, Soni RK, Roda J, Sissons J, Vu LP, Guzman M, Huang K, Laskowski T, Broxmeyer HE, Roodman DG, Perna F. Di Meo F, et al. Among authors: vu lp. Cell Rep Med. 2023 Jul 18;4(7):101110. doi: 10.1016/j.xcrm.2023.101110. Cell Rep Med. 2023. PMID: 37467717 Free PMC article.
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells.
Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu KL, Joshi S, Barin E, Schurer A, Chan M, Chang K, Han GYQ, Pierson AJ, Xiao M, Yang X, Kuehm LM, Hong Y, Nguyen DTT, Chiosis G, Kentsis A, Leslie C, Vu LP, Kharas MG. Herrejon Chavez F, et al. Among authors: vu lp. Nat Commun. 2023 Apr 21;14(1):2290. doi: 10.1038/s41467-023-38001-x. Nat Commun. 2023. PMID: 37085479 Free PMC article.
RNA modifications in hematological malignancies.
Jin Z, MacPherson K, Liu Z, Vu LP. Jin Z, et al. Among authors: vu lp. Int J Hematol. 2023 Jun;117(6):807-820. doi: 10.1007/s12185-023-03576-0. Epub 2023 Mar 16. Int J Hematol. 2023. PMID: 36929506 Review.
28 results