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The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.
Arch Toxicol. 2020 Jul;94(7):2435-2461. doi: 10.1007/s00204-020-02802-6. Epub 2020 Jul 6.
Arch Toxicol. 2020.
PMID: 32632539
Free PMC article.
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.
van der Stel W, Yang H, Vrijenhoek NG, Schimming JP, Callegaro G, Carta G, Darici S, Delp J, Forsby A, White A, le Dévédec S, Leist M, Jennings P, Beltman JB, van de Water B, Danen EHJ.
van der Stel W, et al. Among authors: vrijenhoek ng.
Arch Toxicol. 2022 Jan;96(1):259-285. doi: 10.1007/s00204-021-03160-7. Epub 2021 Oct 13.
Arch Toxicol. 2022.
PMID: 34642769
Free PMC article.
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Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.
Escher SE, Aguayo-Orozco A, Benfenati E, Bitsch A, Braunbeck T, Brotzmann K, Bois F, van der Burg B, Castel J, Exner T, Gadaleta D, Gardner I, Goldmann D, Hatley O, Golbamaki N, Graepel R, Jennings P, Limonciel A, Long A, Maclennan R, Mombelli E, Norinder U, Jain S, Capinha LS, Taboureau OT, Tolosa L, Vrijenhoek NG, van Vugt-Lussenburg BMA, Walker P, van de Water B, Wehr M, White A, Zdrazil B, Fisher C.
Escher SE, et al. Among authors: vrijenhoek ng.
Toxicol In Vitro. 2022 Mar;79:105269. doi: 10.1016/j.tiv.2021.105269. Epub 2021 Oct 29.
Toxicol In Vitro. 2022.
PMID: 34757180
Free article.
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Application of high-throughput transcriptomics for mechanism-based biological read-across of short-chain carboxylic acid analogues of valproic acid.
Vrijenhoek NG, Wehr MM, Kunnen SJ, Wijaya LS, Callegaro G, Moné MJ, Escher SE, Van de Water B.
Vrijenhoek NG, et al.
ALTEX. 2022;39(2):207–220. doi: 10.14573/altex.2107261. Epub 2022 Jan 17.
ALTEX. 2022.
PMID: 35040482
Free article.
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