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Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection.
Garcia-Beltran WF, Claiborne DT, Maldini CR, Phelps M, Vrbanac V, Karpel ME, Krupp KL, Power KA, Boutwell CL, Balazs AB, Tager AM, Altfeld M, Allen TM. Garcia-Beltran WF, et al. Front Immunol. 2021 May 26;12:667393. doi: 10.3389/fimmu.2021.667393. eCollection 2021. Front Immunol. 2021. PMID: 34122425 Free PMC article.
Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice.
Calvet-Mirabent M, Claiborne DT, Deruaz M, Tanno S, Serra C, Delgado-Arévalo C, Sánchez-Cerrillo I, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Allen TM, Buzón MJ, Balazs A, Vrbanac V, Martín-Gayo E. Calvet-Mirabent M, et al. Eur J Immunol. 2022 Mar;52(3):447-461. doi: 10.1002/eji.202149502. Epub 2022 Jan 8. Eur J Immunol. 2022. PMID: 34935145 Free article.
Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment.
Vanuytsel K, Villacorta-Martin C, Lindstrom-Vautrin J, Wang Z, Garcia-Beltran WF, Vrbanac V, Parsons D, Lam EC, Matte TM, Dowrey TW, Kumar SS, Li M, Wang F, Yeung AK, Mostoslavsky G, Dries R, Campbell JD, Belkina AC, Balazs AB, Murphy GJ. Vanuytsel K, et al. Nat Commun. 2022 Mar 1;13(1):1103. doi: 10.1038/s41467-022-28616-x. Nat Commun. 2022. PMID: 35232959 Free PMC article.
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice.
Brady JM, Phelps M, MacDonald SW, Lam EC, Nitido A, Parsons D, Boutros CL, Deal CE, Garcia-Beltran WF, Tanno S, Natarajan H, Ackerman ME, Vrbanac VD, Balazs AB. Brady JM, et al. Among authors: vrbanac vd. Sci Transl Med. 2022 Jul 27;14(655):eabn9662. doi: 10.1126/scitranslmed.abn9662. Epub 2022 Jul 27. Sci Transl Med. 2022. PMID: 35895834 Free PMC article.
De novo hematopoiesis from the fetal lung.
Yeung AK, Villacorta-Martin C, Lindstrom-Vautrin J, Belkina AC, Vanuytsel K, Dowrey TW, Ysasi AB, Bawa P, Wang F, Vrbanac V, Mostoslavsky G, Balazs AB, Murphy GJ. Yeung AK, et al. Blood Adv. 2023 Nov 28;7(22):6898-6912. doi: 10.1182/bloodadvances.2022008347. Blood Adv. 2023. PMID: 37729429 Free PMC article.
HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission.
Usmani SM, Murooka TT, Deruaz M, Koh WH, Sharaf RR, Di Pilato M, Power KA, Lopez P, Hnatiuk R, Vrbanac VD, Tager AM, Allen TM, Luster AD, Mempel TR. Usmani SM, et al. Among authors: vrbanac vd. Cell Host Microbe. 2019 Jan 9;25(1):73-86.e5. doi: 10.1016/j.chom.2018.12.008. Cell Host Microbe. 2019. PMID: 30629922 Free PMC article.
HIV-infected T cells are migratory vehicles for viral dissemination.
Murooka TT, Deruaz M, Marangoni F, Vrbanac VD, Seung E, von Andrian UH, Tager AM, Luster AD, Mempel TR. Murooka TT, et al. Among authors: vrbanac vd. Nature. 2012 Oct 11;490(7419):283-7. doi: 10.1038/nature11398. Epub 2012 Aug 1. Nature. 2012. PMID: 22854780 Free PMC article.
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis.
Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, Kaushal D, Kwon DS. Corleis B, et al. Among authors: vrbanac vd. Cell Rep. 2019 Feb 5;26(6):1409-1418.e5. doi: 10.1016/j.celrep.2019.01.021. Cell Rep. 2019. PMID: 30726727 Free PMC article.
42 results