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Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.
Roymans D, Alnajjar SS, Battles MB, Sitthicharoenchai P, Furmanova-Hollenstein P, Rigaux P, Berg JVD, Kwanten L, Ginderen MV, Verheyen N, Vranckx L, Jaensch S, Arnoult E, Voorzaat R, Gallup JM, Larios-Mora A, Crabbe M, Huntjens D, Raboisson P, Langedijk JP, Ackermann MR, McLellan JS, Vendeville S, Koul A. Roymans D, et al. Among authors: vranckx l. Nat Commun. 2017 Aug 1;8(1):167. doi: 10.1038/s41467-017-00170-x. Nat Commun. 2017. PMID: 28761099 Free PMC article.
Molecular mechanism of respiratory syncytial virus fusion inhibitors.
Battles MB, Langedijk JP, Furmanova-Hollenstein P, Chaiwatpongsakorn S, Costello HM, Kwanten L, Vranckx L, Vink P, Jaensch S, Jonckers TH, Koul A, Arnoult E, Peeples ME, Roymans D, McLellan JS. Battles MB, et al. Among authors: vranckx l. Nat Chem Biol. 2016 Feb;12(2):87-93. doi: 10.1038/nchembio.1982. Epub 2015 Dec 7. Nat Chem Biol. 2016. PMID: 26641933 Free PMC article.
Acquired resistance of Mycobacterium tuberculosis to bedaquiline.
Andries K, Villellas C, Coeck N, Thys K, Gevers T, Vranckx L, Lounis N, de Jong BC, Koul A. Andries K, et al. Among authors: vranckx l. PLoS One. 2014 Jul 10;9(7):e102135. doi: 10.1371/journal.pone.0102135. eCollection 2014. PLoS One. 2014. PMID: 25010492 Free PMC article.
Diarylquinolines target subunit c of mycobacterial ATP synthase.
Koul A, Dendouga N, Vergauwen K, Molenberghs B, Vranckx L, Willebrords R, Ristic Z, Lill H, Dorange I, Guillemont J, Bald D, Andries K. Koul A, et al. Among authors: vranckx l. Nat Chem Biol. 2007 Jun;3(6):323-4. doi: 10.1038/nchembio884. Epub 2007 May 13. Nat Chem Biol. 2007. PMID: 17496888
Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.
Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A. Balemans W, et al. Among authors: vranckx l. Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615276 Free PMC article.
ATP synthase inhibition of Mycobacterium avium is not bactericidal.
Lounis N, Gevers T, Van den Berg J, Vranckx L, Andries K. Lounis N, et al. Among authors: vranckx l. Antimicrob Agents Chemother. 2009 Nov;53(11):4927-9. doi: 10.1128/AAC.00689-09. Epub 2009 Sep 8. Antimicrob Agents Chemother. 2009. PMID: 19738016 Free PMC article.
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