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Page 1
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Jenkins BJ, Blagih J, Ponce-Garcia FM, Canavan M, Gudgeon N, Eastham S, Hill D, Hanlon MM, Ma EH, Bishop EL, Rees A, Cronin JG, Jury EC, Dimeloe SK, Veale DJ, Thornton CA, Vousden KH, Finlay DK, Fearon U, Jones GW, Sinclair LV, Vincent EE, Jones N. Jenkins BJ, et al. Among authors: vousden kh. Cell Metab. 2023 Jul 11;35(7):1132-1146.e9. doi: 10.1016/j.cmet.2023.05.001. Epub 2023 May 24. Cell Metab. 2023. PMID: 37230079 Free article.
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis.
Hennequart M, Pilley SE, Labuschagne CF, Coomes J, Mervant L, Driscoll PC, Legrave NM, Lee Y, Kreuzaler P, Macintyre B, Panina Y, Blagih J, Stevenson D, Strathdee D, Schneider-Luftman D, Grönroos E, Cheung EC, Yuneva M, Swanton C, Vousden KH. Hennequart M, et al. Among authors: vousden kh. Cell Rep. 2023 Jun 27;42(6):112562. doi: 10.1016/j.celrep.2023.112562. Epub 2023 May 26. Cell Rep. 2023. PMID: 37245210 Free article.
Embracing cancer complexity: Hallmarks of systemic disease.
Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, Jamal-Hanjani M, Joyce JA, Kaiser M, Lamia K, Locasale JW, Loi S, Malanchi I, Merad M, Musgrave K, Patel KJ, Quezada S, Wargo JA, Weeraratna A, White E, Winkler F, Wood JN, Vousden KH, Hanahan D. Swanton C, et al. Among authors: vousden kh. Cell. 2024 Mar 28;187(7):1589-1616. doi: 10.1016/j.cell.2024.02.009. Cell. 2024. PMID: 38552609 Review.
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, Häcker G, Hajnóczky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, Jäättelä M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T, Kelly … See abstract for full author list ➔ Vitale I, et al. Among authors: vousden kh. Cell Death Differ. 2023 May;30(5):1097-1154. doi: 10.1038/s41418-023-01153-w. Epub 2023 Apr 26. Cell Death Differ. 2023. PMID: 37100955 Free PMC article. Review.
Reflections on Terri.
Vousden K. Vousden K. Genes Dev. 2023 Jan 1;37(1-2):58. doi: 10.1101/gad.350472.123. Genes Dev. 2023. PMID: 37061950 Free PMC article. No abstract available.
Cycling back to folate metabolism in cancer.
Lee Y, Vousden KH, Hennequart M. Lee Y, et al. Among authors: vousden kh. Nat Cancer. 2024 May 2. doi: 10.1038/s43018-024-00739-8. Online ahead of print. Nat Cancer. 2024. PMID: 38698089 Review.
PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma.
D'Avola A, Legrave N, Tajan M, Chakravarty P, Shearer RL, King HW, Kluckova K, Cheung EC, Clear AJ, Gunawan AS, Zhang L, James LK, MacRae JI, Gribben JG, Calado DP, Vousden KH, Riches JC. D'Avola A, et al. Among authors: vousden kh. J Clin Invest. 2024 Feb 15;134(4):e179917. doi: 10.1172/JCI179917. J Clin Invest. 2024. PMID: 38357928 Free PMC article. No abstract available.
Recovering from the stress of the COVID-19 pandemic.
Lewis SC, Jourdain AA, Schulman BA, Vousden KH, Fabius JM, Liu H. Lewis SC, et al. Among authors: vousden kh. Mol Cell. 2024 Jan 4;84(1):8-11. doi: 10.1016/j.molcel.2023.11.013. Mol Cell. 2024. PMID: 38181764
Phenotypic profiling of solute carriers characterizes serine transport in cancer.
Papalazarou V, Newman AC, Huerta-Uribe A, Legrave NM, Falcone M, Zhang T, McGarry L, Athineos D, Shanks E, Blyth K, Vousden KH, Maddocks ODK. Papalazarou V, et al. Among authors: vousden kh. Nat Metab. 2023 Dec;5(12):2148-2168. doi: 10.1038/s42255-023-00936-2. Epub 2023 Dec 8. Nat Metab. 2023. PMID: 38066114 Free PMC article.
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Caswell DR, Gui P, Mayekar MK, Law EK, Pich O, Bailey C, Boumelha J, Kerr DL, Blakely CM, Manabe T, Martinez-Ruiz C, Bakker B, De Dios Palomino Villcas J, I Vokes N, Dietzen M, Angelova M, Gini B, Tamaki W, Allegakoen P, Wu W, Humpton TJ, Hill W, Tomaschko M, Lu WT, Haderk F, Al Bakir M, Nagano A, Gimeno-Valiente F, de Carné Trécesson S, Vendramin R, Barbè V, Mugabo M, Weeden CE, Rowan A, McCoach CE, Almeida B, Green M, Gomez C, Nanjo S, Barbosa D, Moore C, Przewrocka J, Black JRM, Grönroos E, Suarez-Bonnet A, Priestnall SL, Zverev C, Lighterness S, Cormack J, Olivas V, Cech L, Andrews T, Rule B, Jiao Y, Zhang X, Ashford P, Durfee C, Venkatesan S, Temiz NA, Tan L, Larson LK, Argyris PP, Brown WL, Yu EA, Rotow JK, Guha U, Roper N, Yu J, Vogel RI, Thomas NJ, Marra A, Selenica P, Yu H, Bakhoum SF, Chew SK, Reis-Filho JS, Jamal-Hanjani M, Vousden KH, McGranahan N, Van Allen EM, Kanu N, Harris RS, Downward J, Bivona TG, Swanton C. Caswell DR, et al. Among authors: vousden kh. Nat Genet. 2024 Jan;56(1):60-73. doi: 10.1038/s41588-023-01592-8. Epub 2023 Dec 4. Nat Genet. 2024. PMID: 38049664 Free PMC article.
257 results