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The ERBB network facilitates KRAS-driven lung tumorigenesis.
Kruspig B, Monteverde T, Neidler S, Hock A, Kerr E, Nixon C, Clark W, Hedley A, Laing S, Coffelt SB, Le Quesne J, Dick C, Vousden KH, Martins CP, Murphy DJ. Kruspig B, et al. Among authors: vousden kh. Sci Transl Med. 2018 Jun 20;10(446):eaao2565. doi: 10.1126/scitranslmed.aao2565. Sci Transl Med. 2018. PMID: 29925636 Free PMC article.
Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.
Muller PA, Trinidad AG, Timpson P, Morton JP, Zanivan S, van den Berghe PV, Nixon C, Karim SA, Caswell PT, Noll JE, Coffill CR, Lane DP, Sansom OJ, Neilsen PM, Norman JC, Vousden KH. Muller PA, et al. Among authors: vousden kh. Oncogene. 2013 Mar 7;32(10):1252-65. doi: 10.1038/onc.2012.148. Epub 2012 May 14. Oncogene. 2013. PMID: 22580601 Free PMC article.
Tumor suppression by p53: fall of the triumvirate?
Hock AK, Vousden KH. Hock AK, et al. Among authors: vousden kh. Cell. 2012 Jun 8;149(6):1183-5. doi: 10.1016/j.cell.2012.05.024. Cell. 2012. PMID: 22682240 Free article.
TIGAR is required for efficient intestinal regeneration and tumorigenesis.
Cheung EC, Athineos D, Lee P, Ridgway RA, Lambie W, Nixon C, Strathdee D, Blyth K, Sansom OJ, Vousden KH. Cheung EC, et al. Among authors: vousden kh. Dev Cell. 2013 Jun 10;25(5):463-77. doi: 10.1016/j.devcel.2013.05.001. Epub 2013 May 30. Dev Cell. 2013. PMID: 23726973 Free PMC article.
The role of ubiquitin modification in the regulation of p53.
Hock AK, Vousden KH. Hock AK, et al. Among authors: vousden kh. Biochim Biophys Acta. 2014 Jan;1843(1):137-49. doi: 10.1016/j.bbamcr.2013.05.022. Epub 2013 Jun 3. Biochim Biophys Acta. 2014. PMID: 23742843 Free article. Review.
5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.
Dickens MP, Roxburgh P, Hock A, Mezna M, Kellam B, Vousden KH, Fischer PM. Dickens MP, et al. Among authors: vousden kh. Bioorg Med Chem. 2013 Nov 15;21(22):6868-77. doi: 10.1016/j.bmc.2013.09.038. Epub 2013 Sep 25. Bioorg Med Chem. 2013. PMID: 24113239 Free PMC article.
286 results