Vornov JJ - Search Results

1

Preclinical pharmacology and pharmacokinetics of CERC-301, a GluN2B-selective N-methyl-D-aspartate receptor antagonist.

Garner R, Gopalakrishnan S, McCauley JA, Bednar RA, Gaul SL, Mosser SD, Kiss L, Lynch JJ, Patel S, Fandozzi C, Lagrutta A, Briscoe R, Liverton NJ, Paterson BM, Vornov JJ, Mazhari R. Garner R, et al. Among authors: vornov jj. Pharmacol Res Perspect. 2015 Dec 23;3(6):e00198. doi: 10.1002/prp2.198. eCollection 2015 Dec. Pharmacol Res Perspect. 2015. PMID: 27022470 Free PMC article. Review.

2

Pharmacokinetics and pharmacodynamics of the glutamate carboxypeptidase II inhibitor 2-MPPA show prolonged alleviation of neuropathic pain through an indirect mechanism.

Vornov JJ, Wozniak KM, Wu Y, Rojas C, Rais R, Slusher BS. Vornov JJ, et al. J Pharmacol Exp Ther. 2013 Sep;346(3):406-13. doi: 10.1124/jpet.113.205039. Epub 2013 Jun 17. J Pharmacol Exp Ther. 2013. PMID: 23776202 Free PMC article.

3

Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice.

Vornov JJ, Coyle JT. Vornov JJ, et al. J Neurochem. 1991 Mar;56(3):996-1006. doi: 10.1111/j.1471-4159.1991.tb02020.x. J Neurochem. 1991. PMID: 1671589

4

The orally active glutamate carboxypeptidase II inhibitor E2072 exhibits sustained nerve exposure and attenuates peripheral neuropathy.

Wozniak KM, Wu Y, Vornov JJ, Lapidus R, Rais R, Rojas C, Tsukamoto T, Slusher BS. Wozniak KM, et al. Among authors: vornov jj. J Pharmacol Exp Ther. 2012 Dec;343(3):746-54. doi: 10.1124/jpet.112.197665. Epub 2012 Sep 17. J Pharmacol Exp Ther. 2012. PMID: 22988061

5

Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy.

Thomas AG, Wozniak KM, Tsukamoto T, Calvin D, Wu Y, Rojas C, Vornov J, Slusher BS. Thomas AG, et al. Adv Exp Med Biol. 2006;576:327-37; discussion 361-3. doi: 10.1007/0-387-30172-0_24. Adv Exp Med Biol. 2006. PMID: 16802724 Review.

6

Gastrointestinal delivery of propofol from fospropofol: its bioavailability and activity in rodents and human volunteers.

Wozniak KM, Vornov JJ, Mistry BM, Wu Y, Rais R, Slusher BS. Wozniak KM, et al. Among authors: vornov jj. J Transl Med. 2015 May 29;13:170. doi: 10.1186/s12967-015-0526-9. J Transl Med. 2015. PMID: 26021605 Free PMC article. Clinical Trial.

7

Sustained Accumulation of Microtubule-Binding Chemotherapy Drugs in the Peripheral Nervous System: Correlations with Time Course and Neurotoxic Severity.

Wozniak KM, Vornov JJ, Wu Y, Nomoto K, Littlefield BA, DesJardins C, Yu Y, Lai G, Reyderman L, Wong N, Slusher BS. Wozniak KM, et al. Among authors: vornov jj. Cancer Res. 2016 Jun 1;76(11):3332-9. doi: 10.1158/0008-5472.CAN-15-2525. Epub 2016 Apr 13. Cancer Res. 2016. PMID: 27197173 Free PMC article.

8

FOLH1/GCPII is elevated in IBD patients, and its inhibition ameliorates murine IBD abnormalities.

Rais R, Jiang W, Zhai H, Wozniak KM, Stathis M, Hollinger KR, Thomas AG, Rojas C, Vornov JJ, Marohn M, Li X, Slusher BS. Rais R, et al. Among authors: vornov jj. JCI Insight. 2016 Aug 4;1(12):e88634. doi: 10.1172/jci.insight.88634. JCI Insight. 2016. PMID: 27536732 Free PMC article.

9

Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery.

Wozniak KM, Vornov JJ, Wu Y, Liu Y, Carozzi VA, Rodriguez-Menendez V, Ballarini E, Alberti P, Pozzi E, Semperboni S, Cook BM, Littlefield BA, Nomoto K, Condon K, Eckley S, DesJardins C, Wilson L, Jordan MA, Feinstein SC, Cavaletti G, Polydefkis M, Slusher BS. Wozniak KM, et al. Among authors: vornov jj. Cancer Res. 2018 Feb 1;78(3):817-829. doi: 10.1158/0008-5472.CAN-17-1467. Epub 2017 Nov 30. Cancer Res. 2018. PMID: 29191802 Free PMC article.

10

We're Not "DON" Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine.

Lemberg KM, Vornov JJ, Rais R, Slusher BS. Lemberg KM, et al. Among authors: vornov jj. Mol Cancer Ther. 2018 Sep;17(9):1824-1832. doi: 10.1158/1535-7163.MCT-17-1148. Mol Cancer Ther. 2018. PMID: 30181331 Free PMC article. Review.

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