Von Hoff DD - Search Results

1

Small molecule targeting of transcription-replication conflict for selective chemotherapy.

Gu L, Li M, Li CM, Haratipour P, Lingeman R, Jossart J, Gutova M, Flores L, Hyde C, Kenjić N, Li H, Chung V, Li H, Lomenick B, Von Hoff DD, Synold TW, Aboody KS, Liu Y, Horne D, Hickey RJ, Perry JJP, Malkas LH. Gu L, et al. Among authors: von hoff dd. Cell Chem Biol. 2023 Oct 19;30(10):1235-1247.e6. doi: 10.1016/j.chembiol.2023.07.001. Epub 2023 Aug 1. Cell Chem Biol. 2023. PMID: 37531956 Free PMC article.

2

Single-cell mapping identifies MSI⁺ cells as a common origin for diverse subtypes of pancreatic cancer.

Rajbhandari N, Hamilton M, Quintero CM, Ferguson LP, Fox R, Schürch CM, Wang J, Nakamura M, Lytle NK, McDermott M, Diaz E, Pettit H, Kritzik M, Han H, Cridebring D, Wen KW, Tsai S, Goggins MG, Lowy AM, Wechsler-Reya RJ, Von Hoff DD, Newman AM, Reya T. Rajbhandari N, et al. Among authors: von hoff dd. Cancer Cell. 2023 Nov 13;41(11):1989-2005.e9. doi: 10.1016/j.ccell.2023.09.008. Epub 2023 Oct 5. Cancer Cell. 2023. PMID: 37802055

3

Advanced glycation end product (AGE) targeting antibody SIWA318H is efficacious in preclinical models for pancreatic cancer.

Rossi GR, Jensen A, Ng S, Yin Z, Li A, Misra A, Von Hoff DD, Gruber L, Gruber M, Han H. Rossi GR, et al. Among authors: von hoff dd. Sci Rep. 2023 Oct 7;13(1):16953. doi: 10.1038/s41598-023-44211-6. Sci Rep. 2023. PMID: 37805542 Free PMC article.

4

Intratumoral Malasseziaglobosa Levels Predict Survival and Therapeutic Response to Adjuvant Chemotherapy in Patients With Pancreatic Ductal Adenocarcinoma.

Okuno K, Tokunaga M, Von Hoff D, Kinugasa Y, Goel A; PDAC Biomarker Working Group. Okuno K, et al. Gastroenterology. 2023 Aug;165(2):502-504.e2. doi: 10.1053/j.gastro.2023.04.017. Epub 2023 Apr 28. Gastroenterology. 2023. PMID: 37119937 No abstract available.

5

A Circulating Panel of circRNA Biomarkers for the Noninvasive and Early Detection of Pancreatic Ductal Adenocarcinoma.

Xu C, Jun E, Okugawa Y, Toiyama Y, Borazanci E, Bolton J, Taketomi A, Kim SC, Shang D, Von Hoff D, Zhang G, Goel A. Xu C, et al. Gastroenterology. 2024 Jan;166(1):178-190.e16. doi: 10.1053/j.gastro.2023.09.050. Epub 2023 Oct 14. Gastroenterology. 2024. PMID: 37839499

6

Circulating levels of hydroxylated bradykinin function as an indicator of tissue HIF-1α expression.

Liu Y, Gu Y, Ng S, Deng Z, Lyon CJ, Koay EJ, Ning B, Katz MH, Chiao PJ, Fan J, Han H, Von Hoff D, Hu TY. Liu Y, et al. Sci Bull (Beijing). 2020 Sep 30;65(18):1570-1579. doi: 10.1016/j.scib.2020.04.023. Epub 2020 Apr 18. Sci Bull (Beijing). 2020. PMID: 36738075

7

Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer.

Ng S, Healey AJ, Sontum PC, Kvåle S, Torp SH, Sulheim E, Von Hoff D, Han H. Ng S, et al. J Control Release. 2022 Dec;352:1134-1143. doi: 10.1016/j.jconrel.2022.11.016. Epub 2022 Nov 21. J Control Release. 2022. PMID: 36372388 Free article.

8

First-in-Human Phase I Study of Minnelide in Patients With Advanced Gastrointestinal Cancers: Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity.

Borazanci E, Saluja A, Gockerman J, Velagapudi M, Korn R, Von Hoff D, Greeno E. Borazanci E, et al. Oncologist. 2024 Feb 2;29(2):132-141. doi: 10.1093/oncolo/oyad278. Oncologist. 2024. PMID: 38169017 Free PMC article. Clinical Trial.

9

Increasing Stress to Induce Apoptosis in Pancreatic Cancer via the Unfolded Protein Response (UPR).

Botrus G, Miller RM, Uson Junior PLS, Kannan G, Han H, Von Hoff DD. Botrus G, et al. Among authors: von hoff dd. Int J Mol Sci. 2022 Dec 29;24(1):577. doi: 10.3390/ijms24010577. Int J Mol Sci. 2022. PMID: 36614019 Free PMC article. Review.

10

Improvements in Survival and Clinical Benefit With Gemcitabine as First-Line Therapy for Patients With Advanced Pancreas Cancer: A Randomized Trial.

Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD. Burris HA 3rd, et al. Among authors: von hoff dd. J Clin Oncol. 2023 Dec 20;41(36):5482-5492. doi: 10.1200/JCO.22.02777. J Clin Oncol. 2023. PMID: 38100992

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