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BET bromodomain proteins are required for glioblastoma cell proliferation.
Pastori C, Daniel M, Penas C, Volmar CH, Johnstone AL, Brothers SP, Graham RM, Allen B, Sarkaria JN, Komotar RJ, Wahlestedt C, Ayad NG. Pastori C, et al. Among authors: volmar ch. Epigenetics. 2014 Apr;9(4):611-20. doi: 10.4161/epi.27906. Epub 2014 Feb 19. Epigenetics. 2014. PMID: 24496381 Free PMC article.
Bromodomain inhibitors regulate the C9ORF72 locus in ALS.
Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, Wahlestedt C. Zeier Z, et al. Among authors: volmar ch. Exp Neurol. 2015 Sep;271:241-50. doi: 10.1016/j.expneurol.2015.06.017. Epub 2015 Jun 20. Exp Neurol. 2015. PMID: 26099177 Free PMC article.
Orphan diseases: state of the drug discovery art.
Volmar CH, Wahlestedt C, Brothers SP. Volmar CH, et al. Wien Med Wochenschr. 2017 Jun;167(9-10):197-204. doi: 10.1007/s10354-015-0423-0. Epub 2016 Jan 27. Wien Med Wochenschr. 2017. PMID: 26819216 Free PMC article.
M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.
Volmar CH, Salah-Uddin H, Janczura KJ, Halley P, Lambert G, Wodrich A, Manoah S, Patel NH, Sartor GC, Mehta N, Miles NTH, Desse S, Dorcius D, Cameron MD, Brothers SP, Wahlestedt C. Volmar CH, et al. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9135-E9144. doi: 10.1073/pnas.1707544114. Epub 2017 Oct 9. Proc Natl Acad Sci U S A. 2017. PMID: 29073110 Free PMC article.
54 results