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Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models.
Karpinar DP, Balija MB, Kügler S, Opazo F, Rezaei-Ghaleh N, Wender N, Kim HY, Taschenberger G, Falkenburger BH, Heise H, Kumar A, Riedel D, Fichtner L, Voigt A, Braus GH, Giller K, Becker S, Herzig A, Baldus M, Jäckle H, Eimer S, Schulz JB, Griesinger C, Zweckstetter M. Karpinar DP, et al. Among authors: voigt a. EMBO J. 2009 Oct 21;28(20):3256-68. doi: 10.1038/emboj.2009.257. Epub 2009 Sep 10. EMBO J. 2009. PMID: 19745811 Free PMC article.
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6.
Fiesel FC, Voigt A, Weber SS, Van den Haute C, Waldenmaier A, Görner K, Walter M, Anderson ML, Kern JV, Rasse TM, Schmidt T, Springer W, Kirchner R, Bonin M, Neumann M, Baekelandt V, Alunni-Fabbroni M, Schulz JB, Kahle PJ. Fiesel FC, et al. Among authors: voigt a. EMBO J. 2010 Jan 6;29(1):209-21. doi: 10.1038/emboj.2009.324. Epub 2009 Nov 12. EMBO J. 2010. PMID: 19910924 Free PMC article.
TDP-43-mediated neuron loss in vivo requires RNA-binding activity.
Voigt A, Herholz D, Fiesel FC, Kaur K, Müller D, Karsten P, Weber SS, Kahle PJ, Marquardt T, Schulz JB. Voigt A, et al. PLoS One. 2010 Aug 18;5(8):e12247. doi: 10.1371/journal.pone.0012247. PLoS One. 2010. PMID: 20806063 Free PMC article.
Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.
Reich A, Spering C, Gertz K, Harms C, Gerhardt E, Kronenberg G, Nave KA, Schwab M, Tauber SC, Drinkut A, Harms K, Beier CP, Voigt A, Göbbels S, Endres M, Schulz JB. Reich A, et al. Among authors: voigt a. J Neurosci. 2011 Jan 5;31(1):225-33. doi: 10.1523/JNEUROSCI.2188-10.2011. J Neurosci. 2011. PMID: 21209208 Free PMC article.
Targeted ablation of oligodendrocytes triggers axonal damage.
Ghosh A, Manrique-Hoyos N, Voigt A, Schulz JB, Kreutzfeldt M, Merkler D, Simons M. Ghosh A, et al. Among authors: voigt a. PLoS One. 2011;6(7):e22735. doi: 10.1371/journal.pone.0022735. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818378 Free PMC article.
The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.
Butler EK, Voigt A, Lutz AK, Toegel JP, Gerhardt E, Karsten P, Falkenburger B, Reinartz A, Winklhofer KF, Schulz JB. Butler EK, et al. Among authors: voigt a. PLoS Genet. 2012 Feb;8(2):e1002488. doi: 10.1371/journal.pgen.1002488. Epub 2012 Feb 2. PLoS Genet. 2012. PMID: 22319455 Free PMC article.
TRAP1 rescues PINK1 loss-of-function phenotypes.
Zhang L, Karsten P, Hamm S, Pogson JH, Müller-Rischart AK, Exner N, Haass C, Whitworth AJ, Winklhofer KF, Schulz JB, Voigt A. Zhang L, et al. Among authors: voigt a. Hum Mol Genet. 2013 Jul 15;22(14):2829-41. doi: 10.1093/hmg/ddt132. Epub 2013 Mar 21. Hum Mol Genet. 2013. PMID: 23525905 Free PMC article.
547 results