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The hibernation-derived compound SUL-138 shifts the mitochondrial proteome towards fatty acid metabolism and prevents cognitive decline and amyloid plaque formation in an Alzheimer's disease mouse model.
de Veij Mestdagh CF, Koopmans F, Breiter JC, Timmerman JA, Vogelaar PC, Krenning G, Mansvelder HD, Smit AB, Henning RH, van Kesteren RE. de Veij Mestdagh CF, et al. Among authors: vogelaar pc. Alzheimers Res Ther. 2022 Dec 9;14(1):183. doi: 10.1186/s13195-022-01127-z. Alzheimers Res Ther. 2022. PMID: 36482297 Free PMC article.