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Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.
Kundu S, Xiong A, Spyrou A, Wicher G, Marinescu VD, Edqvist PD, Zhang L, Essand M, Dimberg A, Smits A, Ilan N, Vlodavsky I, Li JP, Forsberg-Nilsson K. Kundu S, et al. Among authors: vlodavsky i. Mol Cancer Res. 2016 Dec;14(12):1243-1253. doi: 10.1158/1541-7786.MCR-16-0223. Epub 2016 Aug 26. Mol Cancer Res. 2016. PMID: 27565180
Heparanase as mediator of angiogenesis: mode of action.
Elkin M, Ilan N, Ishai-Michaeli R, Friedmann Y, Papo O, Pecker I, Vlodavsky I. Elkin M, et al. Among authors: vlodavsky i. FASEB J. 2001 Jul;15(9):1661-3. doi: 10.1096/fj.00-0895fje. FASEB J. 2001. PMID: 11427519 No abstract available.
Human heparanase is localized within lysosomes in a stable form.
Goldshmidt O, Nadav L, Aingorn H, Irit C, Feinstein N, Ilan N, Zamir E, Geiger B, Vlodavsky I, Katz BZ. Goldshmidt O, et al. Among authors: vlodavsky i. Exp Cell Res. 2002 Nov 15;281(1):50-62. doi: 10.1006/excr.2002.5651. Exp Cell Res. 2002. PMID: 12441129
Processing of macromolecular heparin by heparanase.
Gong F, Jemth P, Escobar Galvis ML, Vlodavsky I, Horner A, Lindahl U, Li JP. Gong F, et al. Among authors: vlodavsky i. J Biol Chem. 2003 Sep 12;278(37):35152-8. doi: 10.1074/jbc.M300925200. Epub 2003 Jul 1. J Biol Chem. 2003. PMID: 12837765 Free article.
Heterodimer formation is essential for heparanase enzymatic activity.
Levy-Adam F, Miao HQ, Heinrikson RL, Vlodavsky I, Ilan N. Levy-Adam F, et al. Among authors: vlodavsky i. Biochem Biophys Res Commun. 2003 Sep 5;308(4):885-91. doi: 10.1016/s0006-291x(03)01478-5. Biochem Biophys Res Commun. 2003. PMID: 12927802
Involvement of heparanase in tumor progression and normal differentiation.
Vlodavsky I, Zcharia E, Goldshmidt O, Eshel R, Katz BZ, Minucci S, Kovalchuk O, Penco S, Pisano C, Naggi A, Casu B. Vlodavsky I, et al. Pathophysiol Haemost Thromb. 2003;33 Suppl 1:59-61. doi: 10.1159/000073296. Pathophysiol Haemost Thromb. 2003. PMID: 12955007 Free article. No abstract available.
519 results