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Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel.
Jelínek M, Balušíková K, Daniel P, Němcová-Fürstová V, Kirubakaran P, Jaček M, Wei L, Wang X, Vondrášek J, Ojima I, Kovář J. Jelínek M, et al. Among authors: nemcova furstova v. Toxicol Appl Pharmacol. 2018 May 15;347:79-91. doi: 10.1016/j.taap.2018.04.002. Epub 2018 Apr 4. Toxicol Appl Pharmacol. 2018. PMID: 29625142 Free PMC article.
Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients.
Brynychova V, Ehrlichova M, Hlavac V, Nemcova-Furstova V, Pecha V, Leva J, Trnkova M, Mrhalova M, Kodet R, Vrana D, Kovar J, Vaclavikova R, Gut I, Soucek P. Brynychova V, et al. Among authors: nemcova furstova v. Biomed Pharmacother. 2016 Oct;83:857-864. doi: 10.1016/j.biopha.2016.07.047. Epub 2016 Aug 6. Biomed Pharmacother. 2016. PMID: 27505863
Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target.
Brynychova V, Hlavac V, Ehrlichova M, Vaclavikova R, Nemcova-Furstova V, Pecha V, Trnkova M, Mrhalova M, Kodet R, Vrana D, Gatek J, Bendova M, Vernerova Z, Kovar J, Soucek P. Brynychova V, et al. Among authors: nemcova furstova v. Clin Chem Lab Med. 2017 Jan 1;55(1):111-122. doi: 10.1515/cclm-2016-0271. Clin Chem Lab Med. 2017. PMID: 27327132
17 results