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Activation of the Anaphase Promoting Complex Reverses Multiple Drug Resistant Cancer in a Canine Model of Multiple Drug Resistant Lymphoma.
Arnason TG, MacDonald-Dickinson V, Gaunt MC, Davies GF, Lobanova L, Trost B, Gillespie ZE, Waldner M, Baldwin P, Borrowman D, Marwood H, Vizeacoumar FS, Vizeacoumar FJ, Eskiw CH, Kusalik A, Harkness TAA. Arnason TG, et al. Among authors: vizeacoumar fj, vizeacoumar fs. Cancers (Basel). 2022 Aug 30;14(17):4215. doi: 10.3390/cancers14174215. Cancers (Basel). 2022. PMID: 36077749 Free PMC article.
Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers.
Ward AK, Mellor P, Smith SE, Kendall S, Just NA, Vizeacoumar FS, Sarker S, Phillips Z, Alvi R, Saxena A, Vizeacoumar FJ, Carlsen SA, Anderson DH. Ward AK, et al. Among authors: vizeacoumar fj, vizeacoumar fs. Breast Cancer Res. 2016 Jan 25;18(1):12. doi: 10.1186/s13058-016-0672-x. Breast Cancer Res. 2016. PMID: 26810754 Free PMC article.
Therapeutic relevance of the protein phosphatase 2A in cancer.
Cunningham CE, Li S, Vizeacoumar FS, Bhanumathy KK, Lee JS, Parameswaran S, Furber L, Abuhussein O, Paul JM, McDonald M, Templeton SD, Shukla H, El Zawily AM, Boyd F, Alli N, Mousseau DD, Geyer R, Bonham K, Anderson DH, Yan J, Yu-Lee LY, Weaver BA, Uppalapati M, Ruppin E, Sablina A, Freywald A, Vizeacoumar FJ. Cunningham CE, et al. Among authors: vizeacoumar fj, vizeacoumar fs. Oncotarget. 2016 Sep 20;7(38):61544-61561. doi: 10.18632/oncotarget.11399. Oncotarget. 2016. PMID: 27557495 Free PMC article.
An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer.
Auslander N, Cunningham CE, Toosi BM, McEwen EJ, Yizhak K, Vizeacoumar FS, Parameswaran S, Gonen N, Freywald T, Bhanumathy KK, Freywald A, Vizeacoumar FJ, Ruppin E. Auslander N, et al. Among authors: vizeacoumar fj, vizeacoumar fs. Mol Syst Biol. 2017 Dec 1;13(12):956. doi: 10.15252/msb.20177739. Mol Syst Biol. 2017. PMID: 29196508 Free PMC article.
EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours.
Toosi BM, El Zawily A, Truitt L, Shannon M, Allonby O, Babu M, DeCoteau J, Mousseau D, Ali M, Freywald T, Gall A, Vizeacoumar FS, Kirzinger MW, Geyer CR, Anderson DH, Kim T, Welm AL, Siegel P, Vizeacoumar FJ, Kusalik A, Freywald A. Toosi BM, et al. Among authors: vizeacoumar fj, vizeacoumar fs. Oncogene. 2018 Jul;37(30):4073-4093. doi: 10.1038/s41388-018-0228-x. Epub 2018 Apr 27. Oncogene. 2018. PMID: 29700392 Free PMC article.
Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability.
Jing A, Vizeacoumar FS, Parameswaran S, Haave B, Cunningham CE, Wu Y, Arnold R, Bonham K, Freywald A, Han J, Vizeacoumar FJ. Jing A, et al. Among authors: vizeacoumar fj, vizeacoumar fs. NPJ Syst Biol Appl. 2018 Oct 24;4:38. doi: 10.1038/s41540-018-0074-z. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 30374409 Free PMC article.
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