HLA-DRB1*1501 and response to copolymer-1 therapy in relapsing-remitting multiple sclerosis.
Fusco C, Andreone V, Coppola G, Luongo V, Guerini F, Pace E, Florio C, Pirozzi G, Lanzillo R, Ferrante P, Vivo P, Mini M, Macrì M, Orefice G, Lombardi ML.
Fusco C, et al. Among authors: vivo p.
Neurology. 2001 Dec 11;57(11):1976-9. doi: 10.1212/wnl.57.11.1976.
Neurology. 2001.
PMID: 11739812
Clinical Trial.
BACKGROUND: Copolymer 1 (Cop-1) is a random synthetic amino acid copolymer, effective in the treatment of the relapsing-remitting form of MS (RRMS). In vitro and in vivo studies suggest that the mechanism of Cop-1 involves its binding to major histocompatibility complex cl …
BACKGROUND: Copolymer 1 (Cop-1) is a random synthetic amino acid copolymer, effective in the treatment of the relapsing-remitting form of MS …