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Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism.
Franke M, Daly AF, Palmeira L, Tirosh A, Stigliano A, Trifan E, Faucz FR, Abboud D, Petrossians P, Tena JJ, Vitali E, Lania AG, Gómez-Skarmeta JL, Beckers A, Stratakis CA, Trivellin G. Franke M, et al. Among authors: vitali e. Am J Hum Genet. 2022 Apr 7;109(4):553-570. doi: 10.1016/j.ajhg.2022.02.002. Epub 2022 Feb 23. Am J Hum Genet. 2022. PMID: 35202564 Free PMC article.
Cyclic adenosine 3'-5'-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac).
Vitali E, Peverelli E, Giardino E, Locatelli M, Lasio GB, Beck-Peccoz P, Spada A, Lania AG, Mantovani G. Vitali E, et al. Mol Cell Endocrinol. 2014 Mar 5;383(1-2):193-202. doi: 10.1016/j.mce.2013.12.006. Epub 2013 Dec 25. Mol Cell Endocrinol. 2014. PMID: 24373949
201 results