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From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine.
Petrelli R, Meli M, Vita P, Torquati I, Ferro A, Vodnala M, D'Alessandro N, Tolomeo M, Del Bello F, Kusumanchi P, Franchetti P, Grifantini M, Jayaram HN, Hofer A, Cappellacci L. Petrelli R, et al. Among authors: vita p. Bioorg Med Chem Lett. 2014 Nov 15;24(22):5304-9. doi: 10.1016/j.bmcl.2014.09.046. Epub 2014 Sep 28. Bioorg Med Chem Lett. 2014. PMID: 25304896
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.
Cappellacci L, Franchetti P, Vita P, Petrelli R, Lavecchia A, Jayaram HN, Saiko P, Graser G, Szekeres T, Grifantini M. Cappellacci L, et al. Among authors: vita p. J Med Chem. 2008 Jul 24;51(14):4260-9. doi: 10.1021/jm800205c. Epub 2008 Jun 28. J Med Chem. 2008. PMID: 18588281
Ribose-modified mizoribine analogues: synthesis and biological evaluation.
Franchetti P, Pasqualini M, Cappellacci L, Petrelli R, Vita P, Grifantini M. Franchetti P, et al. Among authors: vita p. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):2023-7. doi: 10.1080/15257770500334673. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438062
5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species.
Cappellacci L, Franchetti P, Vita P, Petrelli R, Lavecchia A, Costa B, Spinetti F, Martini C, Klotz KN, Grifantini M. Cappellacci L, et al. Among authors: vita p. Bioorg Med Chem. 2008 Jan 1;16(1):336-53. doi: 10.1016/j.bmc.2007.09.035. Epub 2007 Sep 22. Bioorg Med Chem. 2008. PMID: 17933541
150 results