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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Vervoort SJ, Welsh SA, Devlin JR, Barbieri E, Knight DA, Offley S, Bjelosevic S, Costacurta M, Todorovski I, Kearney CJ, Sandow JJ, Fan Z, Blyth B, McLeod V, Vissers JHA, Pavic K, Martin BP, Gregory G, Demosthenous E, Zethoven M, Kong IY, Hawkins ED, Hogg SJ, Kelly MJ, Newbold A, Simpson KJ, Kauko O, Harvey KF, Ohlmeyer M, Westermarck J, Gray N, Gardini A, Johnstone RW. Vervoort SJ, et al. Among authors: vissers jha. Cell. 2021 Jun 10;184(12):3143-3162.e32. doi: 10.1016/j.cell.2021.04.022. Epub 2021 May 17. Cell. 2021. PMID: 34004147 Free PMC article.
The Hippo Pathway as a Driver of Select Human Cancers.
Kulkarni A, Chang MT, Vissers JHA, Dey A, Harvey KF. Kulkarni A, et al. Among authors: vissers jha. Trends Cancer. 2020 Sep;6(9):781-796. doi: 10.1016/j.trecan.2020.04.004. Epub 2020 May 20. Trends Cancer. 2020. PMID: 32446746 Review.
Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3.
Thilakasiri P, O'Keefe RN, To SQ, Chisanga D, Eissmann MF, Carli AL, Duscio B, Baloyan D, Dmello RS, Williams D, Mariadason J, Poh AR, Pal B, Kile BT, Vissers JH, Harvey KF, Buchert M, Shi W, Ernst M, Chand AL. Thilakasiri P, et al. Life Sci Alliance. 2023 Nov 13;7(2):e202302411. doi: 10.26508/lsa.202302411. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 37957015 Free PMC article.
21 results