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Low-dose interferon-alpha preconditioning and adoptive cell therapy in patients with metastatic melanoma refractory to standard (immune) therapies: a phase I/II study.
Verdegaal E, van der Kooij MK, Visser M, van der Minne C, de Bruin L, Meij P, Terwisscha van Scheltinga A, Welters MJ, Santegoets S, de Miranda N, Roozen I, Liefers GJ, Kapiteijn E, van der Burg SH. Verdegaal E, et al. Among authors: visser m. J Immunother Cancer. 2020 Mar;8(1):e000166. doi: 10.1136/jitc-2019-000166. J Immunother Cancer. 2020. PMID: 32238469 Free PMC article. Clinical Trial.
Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-alpha.
Verdegaal EM, Visser M, Ramwadhdoebé TH, van der Minne CE, van Steijn JA, Kapiteijn E, Haanen JB, van der Burg SH, Nortier JW, Osanto S. Verdegaal EM, et al. Among authors: visser m. Cancer Immunol Immunother. 2011 Jul;60(7):953-63. doi: 10.1007/s00262-011-1004-8. Epub 2011 Mar 24. Cancer Immunol Immunother. 2011. PMID: 21431917 Free PMC article. Clinical Trial.
Neoantigen landscape dynamics during human melanoma-T cell interactions.
Verdegaal EM, de Miranda NF, Visser M, Harryvan T, van Buuren MM, Andersen RS, Hadrup SR, van der Minne CE, Schotte R, Spits H, Haanen JB, Kapiteijn EH, Schumacher TN, van der Burg SH. Verdegaal EM, et al. Among authors: visser m. Nature. 2016 Aug 4;536(7614):91-5. doi: 10.1038/nature18945. Epub 2016 Jun 27. Nature. 2016. PMID: 27350335
Long-term Survival and Clinical Benefit from Adoptive T-cell Transfer in Stage IV Melanoma Patients Is Determined by a Four-Parameter Tumor Immune Signature.
Melief SM, Visconti VV, Visser M, van Diepen M, Kapiteijn EH, van den Berg JH, Haanen JB, Smit VT, Oosting J, van der Burg SH, Verdegaal EM. Melief SM, et al. Among authors: visser m. Cancer Immunol Res. 2017 Feb;5(2):170-179. doi: 10.1158/2326-6066.CIR-16-0288. Epub 2017 Jan 10. Cancer Immunol Res. 2017. PMID: 28073773
Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4.
van den Bulk J, Verdegaal EME, Ruano D, Ijsselsteijn ME, Visser M, van der Breggen R, Duhen T, van der Ploeg M, de Vries NL, Oosting J, Peeters KCMJ, Weinberg AD, Farina-Sarasqueta A, van der Burg SH, de Miranda NFCC. van den Bulk J, et al. Among authors: visser m. Genome Med. 2019 Dec 30;11(1):87. doi: 10.1186/s13073-019-0697-8. Genome Med. 2019. PMID: 31888734 Free PMC article.
Simplified Monopalmitoyl Toll-like Receptor 2 Ligand Mini-UPam for Self-Adjuvanting Neoantigen-Based Synthetic Cancer Vaccines.
van den Ende TC, Heuts JMM, Gential GPP, Visser M, van de Graaff MJ, Ho NI, Jiskoot W, Valentijn ARPM, Meeuwenoord NJ, Overkleeft HS, Codée JDC, van der Burg SH, Verdegaal EME, van der Marel GA, Ossendorp F, Filippov DV. van den Ende TC, et al. Among authors: visser m. Chembiochem. 2021 Apr 6;22(7):1215-1222. doi: 10.1002/cbic.202000687. Epub 2020 Dec 22. Chembiochem. 2021. PMID: 33180981 Free PMC article.
Phase I/II study protocol to assess safety and efficacy of adoptive cell therapy with anti-PD-1 plus low-dose pegylated-interferon-alpha in patients with metastatic melanoma refractory to standard of care treatments: the ACTME trial.
van der Kooij MK, Verdegaal EME, Visser M, de Bruin L, van der Minne CE, Meij PM, Roozen ICFM, Jonker MA, van den Bosch S, Liefers GJ, Speetjens FM, van der Burg SH, Kapiteijn E. van der Kooij MK, et al. Among authors: visser m. BMJ Open. 2020 Nov 24;10(11):e044036. doi: 10.1136/bmjopen-2020-044036. BMJ Open. 2020. PMID: 33234662 Free PMC article.
2,183 results