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AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.
Santidrián AF, González-Gironès DM, Iglesias-Serret D, Coll-Mulet L, Cosialls AM, de Frias M, Campàs C, González-Barca E, Alonso E, Labi V, Viollet B, Benito A, Pons G, Villunger A, Gil J. Santidrián AF, et al. Among authors: viollet b. Blood. 2010 Oct 21;116(16):3023-32. doi: 10.1182/blood-2010-05-283960. Epub 2010 Jul 27. Blood. 2010. PMID: 20664053 Free article.
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Green AS, Chapuis N, Maciel TT, Willems L, Lambert M, Arnoult C, Boyer O, Bardet V, Park S, Foretz M, Viollet B, Ifrah N, Dreyfus F, Hermine O, Moura IC, Lacombe C, Mayeux P, Bouscary D, Tamburini J. Green AS, et al. Among authors: viollet b. Blood. 2010 Nov 18;116(20):4262-73. doi: 10.1182/blood-2010-02-269837. Epub 2010 Jul 28. Blood. 2010. PMID: 20668229 Free article.
AMPK inhibition in health and disease.
Viollet B, Horman S, Leclerc J, Lantier L, Foretz M, Billaud M, Giri S, Andreelli F. Viollet B, et al. Crit Rev Biochem Mol Biol. 2010 Aug;45(4):276-95. doi: 10.3109/10409238.2010.488215. Crit Rev Biochem Mol Biol. 2010. PMID: 20522000 Free PMC article. Review.
AMPK as a therapeutic target in renal cell carcinoma.
Woodard J, Joshi S, Viollet B, Hay N, Platanias LC. Woodard J, et al. Among authors: viollet b. Cancer Biol Ther. 2010 Dec 1;10(11):1168-77. doi: 10.4161/cbt.10.11.13629. Epub 2010 Dec 1. Cancer Biol Ther. 2010. PMID: 20948309 Free PMC article.
Antagonistic control of muscle cell size by AMPK and mTORC1.
Mounier R, Lantier L, Leclerc J, Sotiropoulos A, Foretz M, Viollet B. Mounier R, et al. Among authors: viollet b. Cell Cycle. 2011 Aug 15;10(16):2640-6. doi: 10.4161/cc.10.16.17102. Epub 2011 Aug 15. Cell Cycle. 2011. PMID: 21799304
354 results