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New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action.
Luque-Navarro PM, Carrasco-Jiménez MP, Goracci L, Paredes JM, Espinar-Barranco L, Valverde-Pozo J, Torretta A, Parisini E, Mariotto E, Marchioro C, Laso A, Marco C, Viola G, Lanari D, López Cara LC. Luque-Navarro PM, et al. Among authors: viola g. Eur J Med Chem. 2023 Jan 15;246:115003. doi: 10.1016/j.ejmech.2022.115003. Epub 2022 Dec 5. Eur J Med Chem. 2023. PMID: 36493617
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).
Schiaffino-Ortega S, Baglioni E, Mariotto E, Bortolozzi R, Serrán-Aguilera L, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Hurtado-Guerrero R, Marco C, Basso G, Viola G, Entrena A, López-Cara LC. Schiaffino-Ortega S, et al. Among authors: viola g. Sci Rep. 2016 Mar 31;6:23793. doi: 10.1038/srep23793. Sci Rep. 2016. PMID: 27029499 Free PMC article.
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.
Carta D, Bortolozzi R, Sturlese M, Salmaso V, Hamel E, Basso G, Calderan L, Quintieri L, Moro S, Viola G, Ferlin MG. Carta D, et al. Among authors: viola g. Eur J Med Chem. 2017 Feb 15;127:643-660. doi: 10.1016/j.ejmech.2016.10.026. Epub 2016 Oct 21. Eur J Med Chem. 2017. PMID: 27823884 Free PMC article.
452 results