Viney NJ - Search Results

1

Lipoprotein(a) Reduction in Persons with Cardiovascular Disease.

Tsimikas S, Karwatowska-Prokopczuk E, Gouni-Berthold I, Tardif JC, Baum SJ, Steinhagen-Thiessen E, Shapiro MD, Stroes ES, Moriarty PM, Nordestgaard BG, Xia S, Guerriero J, Viney NJ, O'Dea L, Witztum JL; AKCEA-APO(a)-LRx Study Investigators. Tsimikas S, et al. Among authors: viney nj. N Engl J Med. 2020 Jan 16;382(3):244-255. doi: 10.1056/NEJMoa1905239. Epub 2020 Jan 1. N Engl J Med. 2020. PMID: 31893580 Clinical Trial.

2

Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study.

Tsimikas S, Viney NJ, Hughes SG, Singleton W, Graham MJ, Baker BF, Burkey JL, Yang Q, Marcovina SM, Geary RS, Crooke RM, Witztum JL. Tsimikas S, et al. Among authors: viney nj. Lancet. 2015 Oct 10;386(10002):1472-83. doi: 10.1016/S0140-6736(15)61252-1. Epub 2015 Jul 22. Lancet. 2015. PMID: 26210642 Clinical Trial.

3

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia.

Gaudet D, Alexander VJ, Baker BF, Brisson D, Tremblay K, Singleton W, Geary RS, Hughes SG, Viney NJ, Graham MJ, Crooke RM, Witztum JL, Brunzell JD, Kastelein JJ. Gaudet D, et al. Among authors: viney nj. N Engl J Med. 2015 Jul 30;373(5):438-47. doi: 10.1056/NEJMoa1400283. N Engl J Med. 2015. PMID: 26222559 Free article. Clinical Trial.

4

Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans.

Graham MJ, Viney N, Crooke RM, Tsimikas S. Graham MJ, et al. J Lipid Res. 2016 Mar;57(3):340-51. doi: 10.1194/jlr.R052258. Epub 2015 Nov 4. J Lipid Res. 2016. PMID: 26538546 Free PMC article. Review.

5

Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials.

Viney NJ, van Capelleveen JC, Geary RS, Xia S, Tami JA, Yu RZ, Marcovina SM, Hughes SG, Graham MJ, Crooke RM, Crooke ST, Witztum JL, Stroes ES, Tsimikas S. Viney NJ, et al. Lancet. 2016 Nov 5;388(10057):2239-2253. doi: 10.1016/S0140-6736(16)31009-1. Epub 2016 Sep 21. Lancet. 2016. PMID: 27665230 Clinical Trial.

6

Temporal variability in lipoprotein(a) levels in patients enrolled in the placebo arms of IONIS-APO(a)_Rx and IONIS-APO(a)-L_Rx antisense oligonucleotide clinical trials.

Marcovina SM, Viney NJ, Hughes SG, Xia S, Witztum JL, Tsimikas S. Marcovina SM, et al. Among authors: viney nj. J Clin Lipidol. 2018 Jan-Feb;12(1):122-129.e2. doi: 10.1016/j.jacl.2017.10.024. Epub 2017 Nov 2. J Clin Lipidol. 2018. PMID: 29174389 Clinical Trial.

7

Relationship between "LDL-C", estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide.

Viney NJ, Yeang C, Yang X, Xia S, Witztum JL, Tsimikas S. Viney NJ, et al. J Clin Lipidol. 2018 May-Jun;12(3):702-710. doi: 10.1016/j.jacl.2018.02.014. Epub 2018 Mar 1. J Clin Lipidol. 2018. PMID: 29574075 Clinical Trial.

8

Relationship of lipoprotein(a) molar concentrations and mass according to lipoprotein(a) thresholds and apolipoprotein(a) isoform size.

Tsimikas S, Fazio S, Viney NJ, Xia S, Witztum JL, Marcovina SM. Tsimikas S, et al. Among authors: viney nj. J Clin Lipidol. 2018 Sep-Oct;12(5):1313-1323. doi: 10.1016/j.jacl.2018.07.003. Epub 2018 Jul 20. J Clin Lipidol. 2018. PMID: 30100157

9

Integrated Assessment of the Clinical Performance of GalNAc₃-Conjugated 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides: I. Human Volunteer Experience.

Crooke ST, Baker BF, Xia S, Yu RZ, Viney NJ, Wang Y, Tsimikas S, Geary RS. Crooke ST, et al. Among authors: viney nj. Nucleic Acid Ther. 2019 Feb;29(1):16-32. doi: 10.1089/nat.2018.0753. Epub 2018 Dec 20. Nucleic Acid Ther. 2019. PMID: 30570431 Free PMC article. Clinical Trial.

10

Potent reduction of plasma lipoprotein (a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis.

Boffa MB, Marar TT, Yeang C, Viney NJ, Xia S, Witztum JL, Koschinsky ML, Tsimikas S. Boffa MB, et al. Among authors: viney nj. J Lipid Res. 2019 Dec;60(12):2082-2089. doi: 10.1194/jlr.P094763. Epub 2019 Sep 24. J Lipid Res. 2019. PMID: 31551368 Free PMC article. Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

25 results

Search Page