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Control of cell death/survival balance by the MET dependence receptor.
Elife. 2020 Feb 24;9:e50041. doi: 10.7554/eLife.50041.
Elife. 2020.
PMID: 32091387
Free PMC article.
MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering.
Montagne R, Baranzelli A, Muharram G, Catherine L, Lesaffre M, Vinchent A, Kherrouche Z, Werkmeister E, Cortot AB, Tulasne D.
Montagne R, et al. Among authors: vinchent a.
Oncotarget. 2017 Feb 14;8(7):11268-11283. doi: 10.18632/oncotarget.14499.
Oncotarget. 2017.
PMID: 28061464
Free PMC article.
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Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors.
Mekki MS, Mougel A, Vinchent A, Paquet C, Copin MC, Leroy C, Kherrouche Z, Bonte JP, Melnyk O, Vicogne J, Tulasne D.
Mekki MS, et al. Among authors: vinchent a.
Oncotarget. 2018 Jun 5;9(43):27039-27058. doi: 10.18632/oncotarget.25472. eCollection 2018 Jun 5.
Oncotarget. 2018.
PMID: 29930749
Free PMC article.
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Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer.
Duplaquet L, Figeac M, Leprêtre F, Frandemiche C, Villenet C, Sebda S, Sarafan-Vasseur N, Bénozène M, Vinchent A, Goormachtigh G, Wicquart L, Rousseau N, Beaussire L, Truant S, Michel P, Sabourin JC, Galateau-Sallé F, Copin MC, Zalcman G, De Launoit Y, Fafeur V, Tulasne D.
Duplaquet L, et al. Among authors: vinchent a.
Mol Cancer Ther. 2019 Jun;18(6):1137-1148. doi: 10.1158/1535-7163.MCT-18-0582. Epub 2019 Mar 29.
Mol Cancer Ther. 2019.
PMID: 30926633
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MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation.
Guérin C, Vinchent A, Fernandes M, Damour I, Laratte A, Tellier R, Estevam GO, Meneboo JP, Villenet C, Descarpentries C, Fraser JS, Figeac M, Cortot AB, Rouleau E, Tulasne D.
Guérin C, et al. Among authors: vinchent a.
bioRxiv [Preprint]. 2023 Nov 7:2023.11.03.565283. doi: 10.1101/2023.11.03.565283.
bioRxiv. 2023.
PMID: 37965202
Free PMC article.
Preprint.
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Transforming properties of MET receptor exon 14 skipping can be recapitulated by loss of the CBL ubiquitin ligase binding site.
Fernandes M, Paget S, Kherrouche Z, Truong MJ, Vinchent A, Meneboo JP, Sebda S, Werkmeister E, Descarpentries C, Figeac M, Cortot AB, Tulasne D.
Fernandes M, et al. Among authors: vinchent a.
FEBS Lett. 2023 Sep;597(18):2301-2315. doi: 10.1002/1873-3468.14702. Epub 2023 Jul 28.
FEBS Lett. 2023.
PMID: 37468447
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MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)-dependent oncogenic driver in vitro and in humanised HGF knock-in mice.
Fernandes M, Hoggard B, Jamme P, Paget S, Truong MJ, Grégoire V, Vinchent A, Descarpentries C, Morabito A, Stanislovas J, Farage E, Meneboo JP, Sebda S, Bouchekioua-Bouzaghou K, Nollet M, Humez S, Perera T, Fromme P, Grumolato L, Figeac M, Copin MC, Tulasne D, Cortot AB, Kermorgant S, Kherrouche Z.
Fernandes M, et al. Among authors: vinchent a.
Mol Oncol. 2023 Nov;17(11):2257-2274. doi: 10.1002/1878-0261.13397. Epub 2023 Jul 14.
Mol Oncol. 2023.
PMID: 36799689
Free PMC article.
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