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A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
Haugaard-Kedström LM, Clemmensen LS, Sereikaite V, Jin Z, Fernandes EFA, Wind B, Abalde-Gil F, Daberger J, Vistrup-Parry M, Aguilar-Morante D, Leblanc R, Egea-Jimenez AL, Albrigtsen M, Jensen KE, Jensen TMT, Ivarsson Y, Vincentelli R, Hamerlik P, Andersen JH, Zimmermann P, Lee W, Strømgaard K. Haugaard-Kedström LM, et al. Among authors: vincentelli r. J Med Chem. 2021 Feb 11;64(3):1423-1434. doi: 10.1021/acs.jmedchem.0c00382. Epub 2021 Jan 27. J Med Chem. 2021. PMID: 33502198
Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.
Vincentelli R, Luck K, Poirson J, Polanowska J, Abdat J, Blémont M, Turchetto J, Iv F, Ricquier K, Straub ML, Forster A, Cassonnet P, Borg JP, Jacob Y, Masson M, Nominé Y, Reboul J, Wolff N, Charbonnier S, Travé G. Vincentelli R, et al. Nat Methods. 2015 Aug;12(8):787-93. doi: 10.1038/nmeth.3438. Epub 2015 Jun 8. Nat Methods. 2015. PMID: 26053890 Free PMC article.
A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
Reynaud S, Ciolek J, Degueldre M, Saez NJ, Sequeira AF, Duhoo Y, Brás JLA, Meudal H, Cabo Díez M, Fernández Pedrosa V, Verdenaud M, Boeri J, Pereira Ramos O, Ducancel F, Vanden Driessche M, Fourmy R, Violette A, Upert G, Mourier G, Beck-Sickinger AG, Mörl K, Landon C, Fontes CMGA, Miñambres Herráiz R, Rodríguez de la Vega RC, Peigneur S, Tytgat J, Quinton L, De Pauw E, Vincentelli R, Servent D, Gilles N. Reynaud S, et al. Among authors: vincentelli r. J Med Chem. 2020 Aug 13;63(15):8250-8264. doi: 10.1021/acs.jmedchem.0c00485. Epub 2020 Jul 16. J Med Chem. 2020. PMID: 32602722
Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth.
Khan Z, Terrien E, Delhommel F, Lefebvre-Omar C, Bohl D, Vitry S, Bernard C, Ramirez J, Chaffotte A, Ricquier K, Vincentelli R, Buc H, Prehaud C, Wolff N, Lafon M. Khan Z, et al. Among authors: vincentelli r. J Biol Chem. 2019 Sep 13;294(37):13755-13768. doi: 10.1074/jbc.RA119.008238. Epub 2019 Jul 25. J Biol Chem. 2019. PMID: 31346033 Free PMC article.
High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery.
Turchetto J, Sequeira AF, Ramond L, Peysson F, Brás JL, Saez NJ, Duhoo Y, Blémont M, Guerreiro CI, Quinton L, De Pauw E, Gilles N, Darbon H, Fontes CM, Vincentelli R. Turchetto J, et al. Among authors: vincentelli r. Microb Cell Fact. 2017 Jan 17;16(1):6. doi: 10.1186/s12934-016-0617-1. Microb Cell Fact. 2017. PMID: 28095880 Free PMC article.
Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.
Gógl G, Biri-Kovács B, Durbesson F, Jane P, Nomine Y, Kostmann C, Bilics V, Simon M, Reményi A, Vincentelli R, Trave G, Nyitray L. Gógl G, et al. Among authors: vincentelli r. J Mol Biol. 2019 Mar 15;431(6):1234-1249. doi: 10.1016/j.jmb.2019.01.038. Epub 2019 Feb 3. J Mol Biol. 2019. PMID: 30726710 Free PMC article.
High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay.
Duhoo Y, Girault V, Turchetto J, Ramond L, Durbesson F, Fourquet P, Nominé Y, Cardoso V, Sequeira AF, Brás JLA, Fontes CMGA, Travé G, Wolff N, Vincentelli R. Duhoo Y, et al. Among authors: vincentelli r. Methods Mol Biol. 2019;2025:439-476. doi: 10.1007/978-1-4939-9624-7_21. Methods Mol Biol. 2019. PMID: 31267466
96 results