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Page 1
Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis.
Yarmolinsky J, Bouras E, Constantinescu A, Burrows K, Bull CJ, Vincent EE, Martin RM, Dimopoulou O, Lewis SJ, Moreno V, Vujkovic M, Chang KM, Voight BF, Tsao PS, Gunter MJ, Hampe J, Pellatt AJ, Pharoah PDP, Schoen RE, Gallinger S, Jenkins MA, Pai RK; PRACTICAL consortium; VA Million Veteran Program; Gill D, Tsilidis KK. Yarmolinsky J, et al. Among authors: vincent ee. Diabetologia. 2023 Aug;66(8):1481-1500. doi: 10.1007/s00125-023-05925-4. Epub 2023 May 12. Diabetologia. 2023. PMID: 37171501 Free PMC article.
Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study.
Papadimitriou N, Bull CJ, Jenab M, Hughes DJ, Bell JA, Sanderson E, Timpson NJ, Smith GD, Albanes D, Campbell PT, Küry S, Le Marchand L, Ulrich CM, Visvanathan K, Figueiredo JC, Newcomb PA, Pai RK, Peters U, Tsilidis KK, Boer JMA, Vincent EE, Mariosa D, Gunter MJ, Richardson TG, Murphy N. Papadimitriou N, et al. Among authors: vincent ee. BMC Med. 2023 Jan 4;21(1):5. doi: 10.1186/s12916-022-02702-9. BMC Med. 2023. PMID: 36600297 Free PMC article.
Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study.
Constantinescu AE, Bull CJ, Jones N, Mitchell R, Burrows K, Dimou N, Bézieau S, Brenner H, Buchanan DD, D'Amato M, Jenkins MA, Moreno V, Pai RK, Um CY, White E, Murphy N, Gunter M, Timpson NJ, Huyghe JR, Vincent EE. Constantinescu AE, et al. Among authors: vincent ee. Int J Cancer. 2024 Jan 1;154(1):94-103. doi: 10.1002/ijc.34691. Epub 2023 Aug 14. Int J Cancer. 2024. PMID: 37578112
A phenome-wide approach to identify causal risk factors for deep vein thrombosis.
Constantinescu AE, Bull CJ, Goudswaard LJ, Zheng J, Elsworth B, Timpson NJ, Moore SF, Hers I, Vincent EE. Constantinescu AE, et al. Among authors: vincent ee. BMC Med Genomics. 2023 Nov 11;16(1):284. doi: 10.1186/s12920-023-01710-9. BMC Med Genomics. 2023. PMID: 37951941 Free PMC article.
Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes.
Bull CJ, Hazelwood E, Legge DN, Corbin LJ, Richardson TG, Lee M, Yarmolinsky J, Smith-Byrne K, Hughes DA, Johansson M, Peters U, Berndt SI, Brenner H, Burnett-Hartman A, Cheng I, Kweon SS, Le Marchand L, Li L, Newcomb PA, Pearlman R, McConnachie A, Welsh P, Taylor R, Lean MEJ, Sattar N, Murphy N, Gunter MJ, Timpson NJ, Vincent EE. Bull CJ, et al. Among authors: vincent ee. EBioMedicine. 2024 Feb;100:104977. doi: 10.1016/j.ebiom.2024.104977. Epub 2024 Jan 29. EBioMedicine. 2024. PMID: 38290287 Free PMC article. Clinical Trial.
The tumor multi-omic landscape of endometrial cancers developed on a germline genetic background of adiposity.
Richenberg G, Francis A, Owen CN, Gray V, Robinson T, Gabriel AA, Lawrenson K, Crosbie EJ, Schildkraut JM, Mckay JD, Gaunt TR, Relton CL, Vincent EE, Kar SP. Richenberg G, et al. Among authors: vincent ee. medRxiv [Preprint]. 2023 Oct 10:2023.10.09.23296765. doi: 10.1101/2023.10.09.23296765. medRxiv. 2023. PMID: 37873386 Free PMC article. Preprint.
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Jenkins BJ, Blagih J, Ponce-Garcia FM, Canavan M, Gudgeon N, Eastham S, Hill D, Hanlon MM, Ma EH, Bishop EL, Rees A, Cronin JG, Jury EC, Dimeloe SK, Veale DJ, Thornton CA, Vousden KH, Finlay DK, Fearon U, Jones GW, Sinclair LV, Vincent EE, Jones N. Jenkins BJ, et al. Among authors: vincent ee. Cell Metab. 2023 Jul 11;35(7):1132-1146.e9. doi: 10.1016/j.cmet.2023.05.001. Epub 2023 May 24. Cell Metab. 2023. PMID: 37230079 Free article.
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition.
Holt AK, Najumudeen AK, Collard TJ, Li H, Millett LM, Hoskin AJ, Legge DN, Mortensson EMH, Flanagan DJ, Jones N, Kollareddy M, Timms P, Hitchings MD, Cronin J, Sansom OJ, Williams AC, Vincent EE. Holt AK, et al. Among authors: vincent ee. Cancer Metab. 2023 Oct 19;11(1):18. doi: 10.1186/s40170-023-00318-y. Cancer Metab. 2023. PMID: 37858256 Free PMC article.
66 results