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CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma.
Burger KL, Fernandez MR, Meads MB, Sudalagunta P, Oliveira PS, Renatino Canevarolo R, Alugubelli RR, Tungsevik A, De Avila G, Silva M, Graeter AI, Dai HA, Vincelette ND, Prabhu A, Magaletti D, Yang C, Li W, Kulkarni A, Hampton O, Koomen JM, Roush WR, Monastyrskyi A, Berglund AE, Silva AS, Cleveland JL, Shain KH. Burger KL, et al. Among authors: vincelette nd. Cancer Res. 2023 Dec 1;83(23):3901-3919. doi: 10.1158/0008-5472.CAN-22-2350. Cancer Res. 2023. PMID: 37702657 Free PMC article.
Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes.
Ward GA, Dalton RP 3rd, Meyer BS, McLemore AF, Aldrich AL, Lam NB, Onimus AH, Vincelette ND, Trinh TL, Chen X, Calescibetta AR, Christiansen SM, Hou HA, Johnson JO, Wright KL, Padron E, Eksioglu EA, List AF. Ward GA, et al. Among authors: vincelette nd. Int J Mol Sci. 2023 Feb 15;24(4):3896. doi: 10.3390/ijms24043896. Int J Mol Sci. 2023. PMID: 36835307 Free PMC article.
Trisomy 8 Defines a Distinct Subtype of Myeloproliferative Neoplasms Driven by the MYC-Alarmin Axis.
Vincelette ND, Yu X, Kuykendall AT, Moon J, Su S, Cheng CH, Sammut R, Razabdouski TN, Nguyen HV, Eksioglu EA, Chan O, Al Ali N, Patel PC, Lee DH, Nakanishi S, Ferreira RB, Hyjek E, Mo Q, Cory S, Lawrence HR, Zhang L, Murphy DJ, Komrokji RS, Lee D, Kaufmann SH, Cleveland JL, Yun S. Vincelette ND, et al. Blood Cancer Discov. 2024 May 7. doi: 10.1158/2643-3230.BCD-23-0210. Online ahead of print. Blood Cancer Discov. 2024. PMID: 38713018
Integrative molecular subtypes of acute myeloid leukemia.
Mo Q, Yun S, Sallman DA, Vincelette ND, Peng G, Zhang L, Lancet JE, Padron E. Mo Q, et al. Among authors: vincelette nd. Blood Cancer J. 2023 May 8;13(1):71. doi: 10.1038/s41408-023-00836-4. Blood Cancer J. 2023. PMID: 37156780 Free PMC article. No abstract available.
MYC overexpression is associated with an early disease progression from MDS to AML.
Gajzer D, Logothetis CN, Sallman DA, Calon G, Babu A, Chan O, Vincelette ND, Volpe VO, Al Ali NH, Basra P, Talati C, Kuykendall AT, Mo Q, Padron E, Sweet K, Komrokji RS, Lancet JE, Yun S, Zhang L. Gajzer D, et al. Among authors: vincelette nd. Leuk Res. 2021 Dec;111:106733. doi: 10.1016/j.leukres.2021.106733. Epub 2021 Oct 21. Leuk Res. 2021. PMID: 34749168 Free PMC article.
Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes.
Ward GA, McGraw KL, Abbas-Aghababazadeh F, Meyer BS, McLemore AF, Vincelette ND, Lam NB, Aldrich AL, Al Ali NH, Padron E, Pinilla-Ibarz J, Masala E, Santini V, Kosmider O, Fontenay M, Fenaux P, Johnson J, Fridley BL, List AF. Ward GA, et al. Among authors: vincelette nd. Blood Adv. 2021 Apr 27;5(8):2216-2228. doi: 10.1182/bloodadvances.2020003475. Blood Adv. 2021. PMID: 33890980 Free PMC article.
TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia.
Yun S, Vincelette ND, Yu X, Watson GW, Fernandez MR, Yang C, Hitosugi T, Cheng CH, Freischel AR, Zhang L, Li W, Hou H, Schaub FX, Vedder AR, Cen L, McGraw KL, Moon J, Murphy DJ, Ballabio A, Kaufmann SH, Berglund AE, Cleveland JL. Yun S, et al. Among authors: vincelette nd. Blood Cancer Discov. 2021 Mar;2(2):162-185. doi: 10.1158/2643-3230.BCD-20-0029. Blood Cancer Discov. 2021. PMID: 33860275 Free PMC article.
CDK2-Mediated Upregulation of TNFα as a Mechanism of Selective Cytotoxicity in Acute Leukemia.
Ding H, Vincelette ND, McGehee CD, Kohorst MA, Koh BD, Venkatachalam A, Meng XW, Schneider PA, Flatten KS, Peterson KL, Correia C, Lee SH, Patnaik M, Webster JA, Ghiaur G, Smith BD, Karp JE, Pratz KW, Li H, Karnitz LM, Kaufmann SH. Ding H, et al. Among authors: vincelette nd. Cancer Res. 2021 May 15;81(10):2666-2678. doi: 10.1158/0008-5472.CAN-20-1504. Epub 2021 Jan 7. Cancer Res. 2021. PMID: 33414171 Free PMC article.
34 results